| Type | Description |
|---|---|
| Definition | DOT1-like, histone H3 methyltransferase (S. cerevisiae) |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes. | 33107819 |
| 2021-03-20 13:33:00 | Maternal DOT1L is dispensable for mouse development. | 33244015 |
| 2021-01-16 15:57:00 | Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function. | 31908356 |
| 2020-11-21 13:29:00 | DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility. | 33060580 |
| 2020-09-05 13:55:00 | Loss of Histone H3 K79 Methyltransferase Dot1l Facilitates Kidney Fibrosis by Upregulating Endothelin 1 through Histone Deacetylase 2. | 31843983 |
| Type | IDs |
|---|---|
| Synonymous | A630076O07, AW907654, Dot1, KMT4, mDot1 |
| Gene |
UniProtKB-ID:
Q6XZL8_MOUSE
UniprotKB:
Q6XZL8
UniParc:
UPI00001C47E4
EMBL:
AY196089,
AC166937
Ensembl:
ENSMUSG00000061589
KO:
mmu:208266
|
| Nucleutide sequences |
EMBL-CDS:
AAP42293.1
Ensembl_TRS:
ENSMUST00000105336
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000100973
RefSeq:
XP_006513492.1,
XP_011241693.1,
XP_006513493.1,
NP_955354.1,
XP_030100834.1,
XP_006513494.1,
XP_011241692.1
|
| Others |
UniRef100:
UniRef100_Q6XZL8
UniRef90:
UniRef90_Q6XZL8
UniRef50:
UniRef50_Q6XZL8
UniGene:
Mm.152371,
Mm.393160
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员