Phldb2 - pleckstrin homology like domain, family B, member 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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208177 Phldb2

基因描述

Type	Description
Definition	pleckstrin homology like domain, family B, member 2

研究结论

Date	Results	Publications
2020-10-03 12:54:00	PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.	30867511
2015-10-31 10:10:00	A transport system, organized by agrin through PI3 kinase, GSK3beta, CLASP2, and LL5beta, for precise delivery of acetylcholine receptor vesicles from subsynaptic nuclei to overlying synaptic membrane was identified at neuromuscular junction membrane.	25589673
2014-10-04 11:45:00	These results provide evidence for an important contribution of the BMP2-PI3K (p55gamma/p110alpha)- PIP3-LL5beta signalling axis in mesenchymal progenitor cell chemotaxis.	24885555

名称对应

Type	IDs
Synonymous	AV253284, C820004H04Rik, LL5b, LL5beta
Gene	UniProtKB-ID: PHLB2_MOUSE UniprotKB: Q8K1N2 UniParc: UPI000024FCE0, UPI000019343C EMBL: AK165251, AK049595, AF506821, BC050915, BC060683 Ensembl: ENSMUSG00000033149 KO: mmu:208177
Nucleutide sequences	EMBL-CDS: AAH60683.1, AAM33635.1, AAH50915.1, BAC33833.1, BAE38105.1 Ensembl_TRS: ENSMUST00000036355, ENSMUST00000076333
Protein sequencees	Ensembl_PRO: ENSMUSP00000046496, ENSMUSP00000075672 RefSeq: XP_036015733.1, XP_036015737.1, XP_036015736.1, XP_036015732.1, XP_006521991.1, XP_006521989.1, XP_036015738.1, XP_006521983.1, XP_006521987.1, XP_006521990.1, NP_001344007.1, XP_036015731.1, XP_036015735.1, XP_030104879.1, XP_036015734.1, NP_700461.2, XP_006521986.1, XP_006521988.1, XP_006521985.1, XP_030104880.1, NP_001239371.1, XP_036015730.1, XP_006521984.1, XP_006521992.1, XP_011244161.1
Others	UniRef100: UniRef100_Q8K1N2 UniRef90: UniRef90_Q8K1N2 UniRef50: UniRef50_Q86SQ0 UniGene: Mm.211477 CCDS: CCDS57031.1, CCDS28202.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
32098917	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. J Biosci Avinash Srivastava , Rakesh K Mishra	2020-01-01	-
30867511	PIP₃-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover. Sci Rep Min-Jue Xie , Yasuyuki Ishikawa , Hideshi Yagi , Tokuichi Iguchi , Yuichiro Oka , Kazuki Kuroda , Keiko Iwata , Hiroshi Kiyonari , Shinji Matsuda , Hideo Matsuzaki , Michisuke Yuzaki , Yugo Fukazawa , Makoto Sato	2019-03-13	-
28671696	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Nat. Neurosci. Jing Li , Wangshu Zhang , Hui Yang , Daniel P Howrigan , Brent Wilkinson , Tade Souaiaia , Oleg V Evgrafov , Giulio Genovese , Veronica A Clementel , Jennifer C Tudor , Ted Abel , James A Knowles , Benjamin M Neale , Kai Wang , Fengzhu Sun , Marcelo P Coba	2017-08-01	-
25589673	CLASP2-dependent microtubule capture at the neuromuscular junction membrane requires LL5Î² and actin for focal delivery of acetylcholine receptor vesicles. Mol. Biol. Cell Sreya Basu , Stefan Sladecek , Isabel Martinez de la PeÃ±a y Valenzuela , Mohammed Akaaboune , Ihor Smal , Katrin Martin , Niels Galjart , Hans Rudolf Brenner	2015-03-01	Phldb2, Clasp2
24885555	BMP2-induced chemotaxis requires PI3K p55Î³/p110Î±-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5Î² recruitment at the cytocortex. BMC Biol. Christian Hiepen , Andreas Benn , Agnieszka Denkis , Ilya Lukonin , Christoph Weise , Jan H Boergermann , Petra Knaus	2014-01-01	Pik3ca, Phldb2, BMP2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735

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