| Type | Description |
|---|---|
| Definition | aph1 homolog B, gamma secretase subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 11:40:00 | Loss of Aph1B is associated with memory deficit. | 26942869 |
| 2017-06-10 10:29:00 | Prostaglandin I2 accumulation in neuronal cells activates and JNK/c-Jun signaling pathways by phosphorylation, which results in APH-1alpha/1beta expression. | 27240539 |
| 2016-05-28 11:13:00 | Abeta oligomers in the cerebrospinal fluid (CSF) further promoted the expression of APH-1alpha/-1beta (by >2.5-fold), which enhances the gamma-cleavage of APP and Abeta deposition during AD progression | 26293690 |
| 2015-08-01 11:04:00 | analysis of hippocampal circuitry via Aph1b-gamma-secretase/neuregulin 1 signalling | 24891237 |
| 2014-02-07 17:09:00 | Upregulation of PS1/gamma-secretase activity may be a risk factor for late onset sporadic Alzheimer's disease. | 22140537 |
| Type | IDs |
|---|---|
| Synonymous | 2310057K14Rik, Aph1c |
| Gene |
UniProtKB-ID:
APH1B_MOUSE
UniprotKB:
Q8C7N7
UniParc:
UPI00000E9145,
UPI00000E99BB
EMBL:
BC079659,
AK049828,
AK028521,
AK154847
Ensembl:
ENSMUSG00000032375
KO:
mmu:208117
|
| Nucleutide sequences |
EMBL-CDS:
BAE32873.1,
BAC33940.1,
BAC25988.1,
AAH79659.1
Ensembl_TRS:
ENSMUST00000034934,
ENSMUST00000168309
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034934,
ENSMUSP00000125816
RefSeq:
XP_006510985.1,
NP_808251.1
|
| Others |
UniRef100:
UniRef100_Q8C7N7
UniRef90:
UniRef90_Q8C7N7
UniRef50:
UniRef50_Q8C7N7
UniGene:
Mm.41291
CCDS:
CCDS23307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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