| Type | Description |
|---|---|
| Definition | endoplasmic reticulum to nucleus signaling 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | IRE1 Endoribonuclease Activity Modulates Hypoxic HIF-1alpha Signaling in Human Endothelial Cells. | 32545307 |
| 2021-03-13 13:21:00 | New insights on human IRE1 tetramer structures based on molecular modeling. | 33060689 |
| 2021-02-20 13:32:00 | KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 alpha-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression. | 32418990 |
| 2021-02-06 13:49:00 | Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish. | 31875595 |
| 2021-01-30 13:02:00 | Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma. | 31869409 |
| Type | IDs |
|---|---|
| Synonymous | IRE1, IRE1P, IRE1a, hIRE1p |
| Gene |
UniProtKB-ID:
ERN1_HUMAN
UniprotKB:
O75460
UniParc:
UPI00003CEFBC,
UPI0000201263
EMBL:
BI912495,
AB209869,
AC005803,
DA254477,
BC130405,
BC130407,
AK292403,
AC025362,
AF059198,
CH471109
Ensembl:
ENSG00000178607
KO:
hsa:2081
|
| Nucleutide sequences |
EMBL-CDS:
BAF85092.1,
EAW94214.1,
BAD93106.1,
AAC25991.1,
AAI30406.1,
AAI30408.1
Ensembl_TRS:
ENST00000606895,
ENST00000433197
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000475519,
ENSP00000401445
RefSeq:
XP_016879837.1,
NP_001424.3,
XP_016879836.1
|
| Others |
UniRef100:
UniRef100_O75460
UniRef90:
UniRef90_O75460
UniRef50:
UniRef50_O75460
UniGene:
Hs.133982,
Hs.700027
CCDS:
CCDS45762.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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