| Type | Description |
|---|---|
| Definition | SET domain containing 1B |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 10:04:00 | Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. | 29916805 |
| 2017-09-30 11:50:00 | Expression profiling of Setd1b(Gdf9) cKO MII oocytes revealed (1) that Setd1b promotes the expression of the major oocyte transcription factors including Obox1, 2, 5, 7, Meis2 and Sall4; and (2) twice as many mRNAs were upregulated than downregulated, suggesting that Setd1b also promotes the expression of negative regulators of oocyte development with multiple Zfp-KRAB factors implicated. | 28619824 |
| 2014-05-03 11:20:00 | The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. | 24550110 |
| Type | IDs |
|---|---|
| Synonymous | AA516740, BC035291, KMT2G, mKIAA1076 |
| Gene |
UniProtKB-ID:
SET1B_MOUSE,
Q3URP1_MOUSE
UniprotKB:
Q8CFT2,
Q3URP1
UniParc:
UPI000163AC7F,
UPI00005AC05F,
UPI000163AC80
EMBL:
BC041681,
AC158114,
BC040775,
BC038367,
AK141316,
AK122435
Ensembl:
ENSMUSG00000038384
KO:
mmu:208043
|
| Nucleutide sequences |
EMBL-CDS:
AAH40775.1,
AAH41681.1,
BAC65717.1,
AAH38367.2,
BAE24647.1
Ensembl_TRS:
ENSMUST00000163030,
ENSMUST00000174836,
ENSMUST00000056053
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000134686,
ENSMUSP00000133933,
ENSMUSP00000134461
RefSeq:
XP_006530301.1,
XP_006530300.1,
NP_001035488.2
|
| Others |
UniRef100:
UniRef100_Q8CFT2,
UniRef100_Q3URP1
UniRef90:
UniRef90_Q3URP1,
UniRef90_Q8CFT2
UniRef50:
UniRef50_Q9UPS6,
UniRef50_Q3URP1
UniGene:
Mm.250391
CCDS:
CCDS59684.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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