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2079 ERH

2079

ERH

ERH mRNA splicing and mitosis factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition ERH mRNA splicing and mitosis factor

研究结论

Date Results Publications
2020-11-28 13:16:00 Knockdown of enhancer of rudimentary homolog inhibits proliferation and metastasis in ovarian cancer by regulating epithelial-mesenchymal transition. 32036222
2020-11-21 13:23:00 ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8. 33035348
2017-09-30 13:41:00 Data suggest that ERH interacts directly in nucleus with C-terminal Arg-Gly-rich region of SAFB1/SAFB2 and this multimer co-localizes in insoluble nuclear fraction; binding of ERH reverses inhibition exerted by SAFB1/SAFB2 on SRPK1. (ERH = enhancer of rudimentary homolog protein; SAFB = scaffold attachment factor B; SRPK1 = splicing kinase SR protein kinase-1) 28627136
2015-10-31 10:07:00 ERH regulation of RNA processing is needed to ensure faithful DNA replication and repair. 26100022
2014-06-07 12:57:00 REVIEW: recent findings indicate that ERH plays an important role in cell cycle through its mRNA splicing activity and is critically required for genomic stability and cancer cell survival 24078386

名称对应

Type IDs
Synonymous DROER
Gene
UniProtKB-ID: ERH_HUMAN, A0A024R6D4_HUMAN
UniprotKB: P84090, A0A024R6D4
UniParc: UPI0000000284
EMBL: BC014301, CH471061, D85758, CR542178, BC071709, U66871, CR450298, BT006877, AK312186
Ensembl: ENSG00000100632
KO: hsa:2079
Nucleutide sequences
EMBL-CDS: CAG29294.1, AAH14301.1, CAG46975.1, BAG35119.1, BAA12865.1, EAW80989.1, AAC51172.1, AAP35523.1, AAH71709.1, EAW80990.1
Gene_ORFName: hCG_21966
Ensembl_TRS: ENST00000557016
Protein sequencees
Ensembl_PRO: ENSP00000451080
RefSeq: NP_004441.1
Others
UniRef100: UniRef100_P84090
UniRef90: UniRef90_P84090
UniRef50: UniRef50_P84090
UniGene: Hs.509791
CCDS: CCDS9794.1

全选

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