| Type | Description |
|---|---|
| Definition | sterol regulatory element binding factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:14:00 | Data suggest that yes-associated protein (YAP) knockdown protects against hepatic steatosis through suppression of the interaction between YAP and sterol regulatory element binding proteins (SREBP-1c and SREBP-2). | 30821074 |
| 2019-12-14 12:04:00 | genetic ablation of SREBP activity in myeloid cells or topical pharmacological inhibition of SREBP improved skin wound healing under homeostatic and chronic inflammatory conditions | 31303399 |
| 2019-03-30 12:07:00 | MicroRNA-98 regulates hepatic cholesterol metabolism by targeting SREBP2 | 30195495 |
| 2018-05-12 10:11:00 | Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis. | 28676202 |
| 2018-04-28 10:03:00 | increase in SREBP-2 directly activates expression of patatin-like phospholipase domain-containing enzyme 8 (PNPLA8) gene, and PNPLA8 associates with autophagosomes and is associated with a decrease in cellular triglyceride | 27767079 |
| Type | IDs |
|---|---|
| Synonymous | AI608257, SREBP-2, SREBP2, SREBP2gc, bHLHd2, lop13, nuc |
| Gene |
UniProtKB-ID:
SRBP2_MOUSE
UniprotKB:
Q3U1N2
UniParc:
UPI00005ACF87,
UPI00001E35D2
EMBL:
AF374267,
AK155857,
AC105358,
AF289715
Ensembl:
ENSMUSG00000022463
KO:
mmu:20788
|
| Nucleutide sequences |
EMBL-CDS:
BAE33463.1,
AAG01859.2,
AAK54763.1
Ensembl_TRS:
ENSMUST00000229336,
ENSMUST00000023100
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023100,
ENSMUSP00000155022
RefSeq:
NP_150087.1,
XP_006520748.1
|
| Others |
UniRef100:
UniRef100_Q3U1N2
UniRef90:
UniRef90_Q3U1N2
UniRef50:
UniRef50_Q12772
UniGene:
Mm.38016
CCDS:
CCDS27683.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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