| Type | Description |
|---|---|
| Definition | serine palmitoyltransferase, long chain base subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-04-09 10:09:00 | The expression of SPT2 was stronger in vascular smooth muscle cells and neointima of carotid arteries from knock-out mice compared to wild-type. | 25978603 |
| 2015-10-24 10:46:00 | Data suggest that overexpression of serine palmitoyltransferase (Sptlc1 and Sptlc2, serine palmitoyltransferase long chain base subunit 1/2) to elevate de novo sphingolipid biosynthesis induces autophagy in the liver. | 25332431 |
| 2013-12-28 11:19:00 | SPTLC2 knockout mice showed decreased ceramide levels in the epidermis, which impaired water-holding capacity and barrier function. | 23633022 |
| 2013-05-25 10:34:00 | Ldlr gene knockout mice with myeloid cell-specific Sptlc2 haploinsufficiency exhibited significantly less atherosclerosis than controls. | 23549085 |
| 2013-02-02 10:54:00 | Data show that LCAT activity was significantly higher in long chain base biosynthesis protein 2 (Sptlc2)+/- and sphingomyelin synthase 2 (Sms2)-/- mice, but markedly lower in ApoE-/- and Ldlr-/- mice. | 22370449 |
| Type | IDs |
|---|---|
| Synonymous | LCB2, LCB2a, Spt2 |
| Gene |
UniProtKB-ID:
SPTC2_MOUSE,
Q542D6_MOUSE
UniprotKB:
P97363,
Q542D6
UniParc:
UPI000000183F
EMBL:
AK089019,
AK159346,
U27455,
BC003227,
X95642,
AK044917
Ensembl:
ENSMUSG00000021036
KO:
mmu:20773
|
| Nucleutide sequences |
EMBL-CDS:
CAA64898.1,
AAC53310.1,
AAH03227.1,
BAC32140.1,
BAC40704.1,
BAE35008.1
Ensembl_TRS:
ENSMUST00000021424
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021424
RefSeq:
NP_035609.1
|
| Others |
UniRef100:
UniRef100_P97363
UniRef90:
UniRef90_O15270
UniRef50:
UniRef50_O15270
UniGene:
Mm.565
CCDS:
CCDS26076.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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