| Type | Description |
|---|---|
| Definition | phosphodiesterase 2A, cGMP-stimulated |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:05:00 | PDE2 regulates membrane potential, respiration and permeability transition of rodent subsarcolemmal cardiac mitochondria. | 31100470 |
| 2019-08-31 11:38:00 | Pde2A is indispensable for heart development because Pde2A knockout embryos show severe atria and ventricular defects. | 29409032 |
| 2016-01-02 10:04:00 | Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by PDE2A. | 26243800 |
| 2015-09-26 11:47:00 | Effect of PDE2 inhibition on stress-induced memory impairment is potentially mediated via modulation of neuroplasticity-related NMDAR-CaMKII-cGMP/cAMP signaling. | 25442113 |
| 2015-02-21 11:56:00 | We conclude that increased AM PDE2A is an important negative regulator of macrophage iNOS expression. | 25063878 |
| Type | IDs |
|---|---|
| Synonymous | CGS-PDE, cGSPDE |
| Gene |
UniProtKB-ID:
PDE2A_MOUSE,
A0A1B0GRJ9_MOUSE,
Q3TYK5_MOUSE,
Q3TYU3_MOUSE,
Q5PR72_MOUSE
UniprotKB:
Q922S4,
A0A1B0GRJ9,
Q3TYK5,
Q3TYU3,
Q5PR72
UniParc:
UPI00005AD1F9,
UPI00003BF7A2,
UPI0000218900,
UPI00005AD1BF,
UPI00005AD25E,
UPI00001F5C32,
UPI0000428E2D
EMBL:
AC129079,
BC006845,
AK170573,
BC057029,
BC086800,
AK158560,
AK159012,
AK158354,
BC029810,
AC129609
Ensembl:
ENSMUSG00000110195
KO:
mmu:207728
|
| Nucleutide sequences |
EMBL-CDS:
AAH29810.1,
BAE34768.1,
BAE41887.1,
AAH06845.1,
BAE34558.1,
BAE34469.1,
AAH86800.1
Ensembl_TRS:
ENSMUST00000163751,
ENSMUST00000209537,
ENSMUST00000166652,
ENSMUST00000211368
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131553,
ENSMUSP00000147553,
ENSMUSP00000147847,
ENSMUSP00000127521
RefSeq:
XP_006507587.1,
NP_001230687.1,
XP_006507592.1,
XP_011240020.1,
NP_001137320.1,
NP_001230686.1,
XP_036008746.1,
XP_036008745.1,
XP_006507586.1,
XP_030098167.1,
XP_006507588.1,
NP_001137321.1,
XP_036008744.1,
NP_001008548.1,
XP_006507589.1,
XP_006507591.1
|
| Others |
UniRef100:
UniRef100_Q3TYU3,
UniRef100_A0A1B0GRJ9,
UniRef100_Q922S4,
UniRef100_Q3TYK5,
UniRef100_Q5PR72
UniRef90:
UniRef90_Q922S4-3,
UniRef90_Q3TYU3,
UniRef90_Q922S4
UniRef50:
UniRef50_Q922S4-3,
UniRef50_Q3TYU3,
UniRef50_Q922S4
UniGene:
Mm.247564
CCDS:
CCDS52330.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员