| Type | Description |
|---|---|
| Definition | ETS2 repressor factor |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:22:00 | Here we describe a boy and his mother with different craniosynostosis patterns, but both with verified intracranial hypertension and heterozygosity for a truncating variant of ERF c.1201_1202delAA (p.Lys401Glufs*10). | 32370745 |
| 2020-04-25 12:34:00 | Mutation in the ERF gene is associated with craniosynostosis syndrome. | 30758909 |
| 2018-06-30 10:59:00 | Systematic genomic sequencing of prostate cancer in African-American men revealed new insights into prostate cancer, including the identification of ERF as a prostate cancer gene; somatic copy-number alteration differences; and uncommon PIK3CA and PTEN alterations. This study highlights the importance of inclusion of underrepresented minorities in cancer sequencing studies. | 28515055 |
| 2018-04-21 11:10:00 | Identification of novel prostate cancer drivers, ERF, CREB3L1, and POU2F2, using RegNetDriver, a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network. | 28750683 |
| 2017-11-25 14:30:00 | data provide evidence that the oncogenicity of ERG is mediated, in part, by competition with ERF and they raise the larger question of whether other gain-of-function oncogenic transcription factors might also inactivate endogenous tumour suppressors | 28614298 |
| Type | IDs |
|---|---|
| Synonymous | CHYTS, CRS4, PE-2, PE2 |
| Gene |
UniProtKB-ID:
ERF_HUMAN,
A0A024R0L4_HUMAN
UniprotKB:
P50548,
A0A024R0L4
UniParc:
UPI0000EE6DD0,
UPI000000106F
EMBL:
AC006486,
U15655,
AK314278,
CH471126,
BC022231,
AB209271,
AK297666
Ensembl:
ENSG00000105722
KO:
hsa:2077
|
| Nucleutide sequences |
EMBL-CDS:
BAD92508.1,
AAH22231.1,
AAA86686.1,
AAD11987.1,
EAW57116.1,
EAW57118.1,
BAG36938.1,
BAH12646.1,
EAW57117.1
Gene_ORFName:
hCG_20354
Ensembl_TRS:
ENST00000222329,
ENST00000440177
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000388173,
ENSP00000222329
RefSeq:
NP_001299585.1,
XP_016881957.1,
XP_016881958.1,
NP_001287964.1,
NP_001295331.1,
NP_006485.2
|
| Others |
UniRef100:
UniRef100_P50548
UniRef90:
UniRef90_P50548
UniRef50:
UniRef50_P50548
UniGene:
Hs.655969
CCDS:
CCDS77308.1,
CCDS12600.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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