| Type | Description |
|---|---|
| Definition | sepiapterin reductase |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:09:00 | Our results suggest that the hypertension with fluctuation and bradycardia of Spr(-/-) mice would be caused by an imbalance of sympathetic and parasympathetic input and impaired nitric oxide production in endothelial cells. | 28320892 |
| 2013-09-14 10:42:00 | SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms | 23640889 |
| 2011-03-05 11:09:00 | biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21 | 21062748 |
| 2010-01-21 00:00:00 | These data suggest an essential role of SPR in the biosynthesis of BH4, and that the SPR gene could be a candidate gene for PARK3. | 18201550 |
| Type | IDs |
|---|---|
| Synonymous | AA409688, Gm10328 |
| Gene |
UniProtKB-ID:
Q91XH5_MOUSE
UniprotKB:
Q91XH5
UniParc:
UPI000002951B
EMBL:
BC010400,
AC153373,
BC054423
Ensembl:
ENSMUSG00000033735
KO:
mmu:20751
|
| Nucleutide sequences |
EMBL-CDS:
AAH10400.1,
AAH54423.1
Ensembl_TRS:
ENSMUST00000045986,
ENSMUST00000204757
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048111,
ENSMUSP00000145412
RefSeq:
NP_035597.2
|
| Others |
UniRef100:
UniRef100_Q91XH5
UniRef90:
UniRef90_Q64105
UniRef50:
UniRef50_Q64105
UniGene:
Mm.28393
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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