| Type | Description |
|---|---|
| Definition | speckle-type POZ protein |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:31:00 | Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. | 33531470 |
| 2019-11-23 10:50:00 | SPOP is a key regulator of emergency hematopoiesis and inflammation sensing in the bone marrow. | 31406379 |
| 2019-07-27 10:53:00 | SPOP is required for embryo implantation, endometrial decidualization, and uterine health in the mouse | 29546395 |
| 2019-05-11 10:53:00 | no evidence that ERG is an effector of SPOP mutation in human prostate cancer or mouse models. | 29202479 |
| 2018-04-14 10:28:00 | loss of Spop, but not Spopl, disrupts chondrocyte hypertrophy and osteoblast differentiation in the mouse, suggesting the requirement for Spop-mediated protein degradation in mouse skeletal development; overexpressed Spop targets both Gli3FL and Gli3R for ubiquitination and degradation and Spop is an important positive regulator of Ihh signaling and skeletal development | 27930311 |
| Type | IDs |
|---|---|
| Synonymous | AI315626, Pcif1, TEF2 |
| Gene |
UniProtKB-ID:
SPOP_MOUSE,
Q9DBZ2_MOUSE
UniprotKB:
Q6ZWS8,
Q9DBZ2
UniParc:
UPI00000284BC,
UPI0000003F5C
EMBL:
AY538613,
AK159482,
AK004669,
BC045205,
AK028201,
AL662875,
AK166581,
BC043131,
AK030746,
AB071989
Ensembl:
ENSMUSG00000057522
KO:
mmu:20747
|
| Nucleutide sequences |
EMBL-CDS:
AAH45205.1,
AAT08952.1,
BAC27114.1,
BAC25809.1,
BAE38870.1,
BAE35119.1,
BAB68542.1,
AAH43131.1,
BAB23458.1
Ensembl_TRS:
ENSMUST00000107724,
ENSMUST00000107722
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103352,
ENSMUSP00000103350
RefSeq:
NP_001346036.1,
NP_079563.2
|
| Others |
UniRef100:
UniRef100_O43791,
UniRef100_Q9DBZ2
UniRef90:
UniRef90_O43791,
UniRef90_Q9DBZ2
UniRef50:
UniRef50_O43791,
UniRef50_W5LYD1
UniGene:
Mm.285454
CCDS:
CCDS36286.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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