| Type | Description |
|---|---|
| Definition | serine protease inhibitor, Kunitz type 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 10:16:00 | ese results suggest that serine proteases promote intestinal carcinogenesis through activation of PAR-2, and that HAI-1 plays a critical tumor suppressor role as an inhibitor of matriptase, kallikreins, and other PAR-2 activating proteases. | 31997435 |
| 2020-01-25 11:01:00 | We propose that Spint1 contributes to the tumor-suppressive function of HIF-2a in tumor-associated macrophages in breast tumor development | 31436357 |
| 2019-03-30 11:22:00 | Grhl2 regulation of SPINT1 expression controls salivary gland development | 30193734 |
| 2018-02-17 10:56:00 | Results suggest that insufficient hepatocyte growth factor activator inhibitor type 1 (HAI-1) function promotes intestinal carcinogenesis by activating nuclear factor-kappaB (NF-kappaB) signaling. | 27612426 |
| 2016-12-24 10:12:00 | By completing our structural characterization of the previously unknown N-terminal region of HAI-1, we provide new insight into the interplay between tertiary structure and the inhibitory activity of a multidomain protease inhibitor | 27189939 |
| Type | IDs |
|---|---|
| Synonymous | HAI-1 |
| Gene |
UniProtKB-ID:
SPIT1_MOUSE
UniprotKB:
Q9R097
UniParc:
UPI0000022B75
EMBL:
BC005769,
AL929318,
CH466519,
AF099018
Ensembl:
ENSMUSG00000027315
KO:
mmu:20732
|
| Nucleutide sequences |
EMBL-CDS:
AAH05769.1,
AAF02490.1,
EDL27946.1
Ensembl_TRS:
ENSMUST00000110816,
ENSMUST00000110817,
ENSMUST00000028783
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106440,
ENSMUSP00000106441,
ENSMUSP00000028783
RefSeq:
NP_058603.2,
XP_006499125.1,
XP_030104818.1
|
| Others |
UniRef100:
UniRef100_Q9R097
UniRef90:
UniRef90_Q9R097
UniRef50:
UniRef50_Q9R097
UniGene:
Mm.104955
CCDS:
CCDS16597.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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