Spic - Spi-C transcription factor (Spi-1/PU.1 related)-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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20728 Spic

基因描述

Type	Description
Definition	Spi-C transcription factor (Spi-1/PU.1 related)

研究结论

Date	Results	Publications
2021-03-27 14:42:00	Opposing Roles for the Related ETS-Family Spi-B and Spi-C in Regulating Differentiation and Function.	32457757
2020-09-19 16:26:00	RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early through Activation of a SPIC-BCLAF1 Complex.	31644907
2020-08-15 19:05:00	Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C.	31506384
2015-06-20 12:09:00	These results indicate a novel role for Spi-C as a negative regulator of B cell development and function.	25769919
2014-06-07 12:56:00	Study reports that Spic regulated the development of F4/80(+)VCAM1(+) bone marrow macrophages (BMM) and that Spic expression in BMM and red pulp macrophages development was induced by heme, a metabolite of erythrocyte degradation.	24630724

名称对应

Type	IDs
Synonymous	AU019198, C76795, Prf, Spi-C
Gene	UniProtKB-ID: SPIC_MOUSE UniprotKB: Q6P3D7 UniParc: UPI00001E5367, UPI00005AD092 EMBL: AF098863, CH466539, AK156892, AK156024, BC064038, AK137522, AK157188 Ensembl: ENSMUSG00000004359 KO: mmu:20728
Nucleutide sequences	EMBL-CDS: BAE33887.1, AAD16228.2, AAH64038.1, EDL21490.1, BAE33549.1, BAE33991.1, BAE23394.1 Ensembl_TRS: ENSMUST00000004473
Protein sequencees	Ensembl_PRO: ENSMUSP00000004473 RefSeq: NP_035591.3
Others	UniRef100: UniRef100_Q6P3D7 UniRef90: UniRef90_Q6P3D7 UniRef50: UniRef50_Q6P3D7 UniGene: Mm.21642 CCDS: CCDS36023.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
32610126	Counter Regulation of Spic by NF-ÎºB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages. Cell Rep Zahidul Alam , Samir Devalaraja , Minghong Li , Tsun Ki Jerrick To , Ian W Folkert , Erick Mitchell-Velasquez , Mai T Dang , Patricia Young , Christopher J Wilbur , Michael A Silverman , Xinyuan Li , Youhai H Chen , Paul T Hernandez , Aritra Bhattacharyya , Mallar Bhattacharya , Matthew H Levine , Malay Haldar	2020-06-30	-
32272082	Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages. Immunity Yuning Lu , Gemma Basatemur , Ian C Scott , Davide Chiarugi , Marc Clement , James Harrison , Ravin Jugdaohsingh , Xian Yu , Stephen A Newland , Helen E Jolin , Xuan Li , Xiao Chen , Monika Szymanska , Guttorm Haraldsen , Gaby Palmer , Padraic G Fallon , E Suzanne Cohen , Andrew N J McKenzie , Ziad Mallat	2020-05-19	-
32457757	Opposing Roles for the Related ETS-Family Transcription Factors Spi-B and Spi-C in Regulating B Cell Differentiation and Function. Front Immunol Anne-Sophie LaramÃ©e , Hannah Raczkowski , Peng Shao , Carolina Batista , Devanshi Shukla , Li Xu , S M Mansour Haeryfar , Yodit Tesfagiorgis , Steven Kerfoot , Rodney DeKoter	2020-01-01	-
31644907	RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex. Cell Rep Deepti Soodgupta , Lynn S White , Wei Yang , Rachel Johnston , Jared M Andrews , Masako Kohyama , Kenneth M Murphy , Nima Mosammaparast , Jacqueline E Payton , Jeffrey J Bednarski	2019-10-22	-
31506384	Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C. Sci Signal Laura F Bennett , Chang Liao , Michael D Quickel , Beng San Yeoh , Matam Vijay-Kumar , Pamela Hankey-Giblin , K Sandeep Prabhu , Robert F Paulson	2019-09-10	-
30026265	Mammalian embryo comparison identifies novel pluripotency genes associated with the naÃ¯ve or primed state. Biol Open Andreia S Bernardo , Alice Jouneau , Hendrik Marks , Philip Kensche , Julianna Kobolak , Kristine Freude , Vanessa Hall , Anita Feher , Zsuzsanna Polgar , Chiara Sartori , Istvan Bock , Claire Louet , Tiago Faial , Hindrik H D Kerstens , Camille Bouissou , Gregory Parsonage , Kaveh Mashayekhi , James C Smith , Giovanna Lazzari , Poul Hyttel , Hendrik G Stunnenberg , Martijn Huynen , Roger A Pedersen , Andras Dinnyes	2018-08-17	-
30061415	Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles. Proc. Natl. Acad. Sci. U.S.A. Hisako Kayama , Masako Kohyama , Daisuke Okuzaki , Daisuke Motooka , Soumik Barman , Ryu Okumura , Masato Muneta , Katsuaki Hoshino , Izumi Sasaki , Wataru Ise , Hiroshi Matsuno , Junichi Nishimura , Tomohiro Kurosaki , Shota Nakamura , Hisashi Arase , Tsuneyasu Kaisho , Kiyoshi Takeda	2018-08-14	-
27543439	The macrophage contribution to stress erythropoiesis: when less is enough. Blood Tatiana Ulyanova , Susan R Phelps , Thalia Papayannopoulou	2016-09-29	-
26834154	RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. J. Exp. Med. Jeffrey J Bednarski , Ruchi Pandey , Emily Schulte , Lynn S White , Bo-Ruei Chen , Gabriel J Sandoval , Masako Kohyama , Malay Haldar , Andrew Nickless , Amanda Trott , Genhong Cheng , Kenneth M Murphy , Craig H Bassing , Jacqueline E Payton , Barry P Sleckman	2016-02-08	-
26097038	Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg. Yoichi Ohta , Takahiro Okabe , Colleen Larmour , Agnese Di Rocco , Marijke W Maijenburg , Amanda Phillips , Nancy A Speck , Shigeyuki Wakitani , Takashi Nakamura , Yoshihiko Yamada , Motomi Enomoto-Iwamoto , Maurizio Pacifici , Masahiro Iwamoto	2015-10-01	-

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