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2072 ERCC4

2072

ERCC4

ERCC excision repair 4, endonuclease catalytic subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition ERCC excision repair 4, endonuclease catalytic subunit

研究结论

Date Results Publications
2021-02-06 13:51:00 DNA base excision repair and nucleotide excision repair proteins in malignant salivary gland tumors. 33202356
2020-08-22 15:26:00 Impact of XPF rs2276466 polymorphism on cancer susceptibility: a meta-analysis. 31040199
2020-05-30 12:57:00 Our results confirm its dependence on XPA in NER and furthermore show that its engagement in ICLR is dependent on FANCD2. Interestingly, we find that two ICLR-defective XPF mutants (R689S and S786F) are less well recruited to ICLs. These studies highlight the differential mechanisms that regulate ERCC1-XPF activity in DNA repair 31392348
2020-05-30 11:21:00 DCAF7 is a novel regulator of ERCC1-XPF protein level and cellular nucleotide excision repair activity. 31493872
2020-05-23 10:53:00 TIP60 directly acetylates XPF at Lysine 911 following ultraviolet irradiation and that this acetylation is required for XPF-ERCC1 complex assembly and subsequent activation. 32034146

名称对应

Type IDs
Synonymous ERCC11, FANCQ, RAD1, XFEPS, XPF
Gene
UniProtKB-ID: XPF_HUMAN, B4DXD8_HUMAN, A0A1W1GSK9_HUMAN
UniprotKB: Q92889, B4DXD8, A0A1W1GSK9
UniParc: UPI0000161BBF, UPI0001565772, UPI00017A80C5
EMBL: BC142631, CH471112, AF491814, AC010401, AK301930, L77890, LT827130, AK289726, U64315
Ensembl: ENSG00000175595
KO: hsa:2072
Nucleutide sequences
EMBL-CDS: AAI42632.1, AAB50174.1, AAB07689.1, BAF82415.1, AAL91593.1, BAG63350.1, EAW85117.1, SLM22340.1
Gene_ORFName: hCG_37239
Ensembl_TRS: ENST00000575156, ENST00000311895
Protein sequencees
Ensembl_PRO: ENSP00000459933, ENSP00000310520
RefSeq: NP_005227.1, XP_011520729.1, XP_016878532.1, XP_011520726.1
Others
UniRef100: UniRef100_B4DXD8, UniRef100_Q92889
UniRef90: UniRef90_Q92889
UniRef50: UniRef50_Q92889
UniGene: Hs.567265
CCDS: CCDS32390.1

全选

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