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20716 Serpina3n

20716

Serpina3n

serine (or cysteine) peptidase inhibitor, clade A, member 3N

protein-coding

Mus musculus

基因描述

Type Description
Definition serine (or cysteine) peptidase inhibitor, clade A, member 3N

研究结论

Date Results Publications
2021-04-13 10:13:00 A Potential Role for SerpinA3N in Acetaminophen-Induced Hepatotoxicity. 33436521
2021-03-13 13:18:00 Serpina3n is closely associated with fibrotic procession and knockdown ameliorates bleomycin-induced pulmonary fibrosis. 32900484
2019-11-30 11:04:00 Exposure of mice to high-fat diet (HFD) over a more prolonged period to drive systemic inflammation also caused obesity. RNAseq used to assess hypothalamic inflammation in these mice showed increased hypothalamic expression of Serpina3n and Socs3 in response to HFD, with few other genes altered. 30353127
2019-04-20 10:49:00 Serpina3n as the most female osteoblast-dominant gene. Serpina3n exerts a suppression of the osteoblast phenotypes such as Col1a1 expression and ALP activity in differentiated osteoblasts, which might partly explain sex differences of the osteoblast phenotypes in mice. 30304388
2015-08-08 10:35:00 SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase 25915831

名称对应

Type IDs
Synonymous Spi2-2, Spi2.2, Spi2/eb.4
Gene
UniProtKB-ID: G3X8T9_MOUSE
UniprotKB: G3X8T9
UniParc: UPI0000021AF2
EMBL: AC117194
Ensembl: ENSMUSG00000021091
KO: mmu:20716
Nucleutide sequences
Ensembl_TRS: ENSMUST00000021506
Protein sequencees
Ensembl_PRO: ENSMUSP00000021506
RefSeq: XP_036013174.1, XP_011242348.1, NP_033278.2
Others
UniRef100: UniRef100_G3X8T9
UniRef90: UniRef90_Q91WP6
UniRef50: UniRef50_Q91WP6
UniGene: Mm.482074

全选

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研究热度

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