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2070 EYA4

2070

EYA4

EYA transcriptional coactivator and phosphatase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition EYA transcriptional coactivator and phosphatase 4

研究结论

Date Results Publications
2020-12-05 12:58:00 Insights into the pathophysiology of DFNA10 hearing loss associated with novel EYA4 variants. 32277154
2020-11-21 13:33:00 Prevalence and clinical features of hearing loss caused by EYA4 variants. 32107406
2020-08-01 12:19:00 EYA4 is a novel tumour suppressor in HCC and a new prognostic biomarker and therapeutic target in HCC. 30957411
2020-04-18 11:39:00 Result show that EYA4 expression is regulated by miR626 which targets its 3'UTR in bladder cancer cells. 31101108
2019-10-12 12:43:00 Study reports that EYA4 suppressed hepatocellular carcinoma (HCC) tumor cell growth by reducing the nuclear translocation of beta-catenin by dephosphorylation at Ser552, thereby suppressing the transcription of MYCBP which was induced by beta-catenin/LEF1 binding to the promoter of MYCBP. 31385398

名称对应

Type IDs
Synonymous CMD1J, DFNA10
Gene
UniProtKB-ID: EYA4_HUMAN, F2Z2Y1_HUMAN, Q96CJ7_HUMAN, A0A0S2Z3V9_HUMAN, B4DRQ6_HUMAN, B4DIV6_HUMAN, A0A0S2Z3Q2_HUMAN
UniprotKB: O95677, F2Z2Y1, Q96CJ7, A0A0S2Z3V9, B4DRQ6, B4DIV6, A0A0S2Z3Q2
UniParc: UPI00017A7A59, UPI0001AE72E3, UPI000013D649, UPI000016187A, UPI00017A7287, UPI0000231BCA, UPI0001F782C3, UPI0000551C7D, UPI0000074565
EMBL: AL024497, Y17114, BC014193, AJ007994, AK295798, AL356242, KF458286, BC041063, AL450270, AL121959, AJ007993, AK301950, Y17847, KU178044, AK299378, KF458290, KU178045
Ensembl: ENSG00000112319
KO: hsa:2070
Nucleutide sequences
EMBL-CDS: AAH41063.1, CAA76636.1, CAA76891.1, CAA07817.1, BAH13593.1, CAA07816.1, AAH14193.2, ALQ33502.1, BAG61368.1, BAG58618.1, ALQ33503.1
Ensembl_TRS: ENST00000452339, ENST00000431403, ENST00000355167, ENST00000355286, ENST00000531901
Protein sequencees
Ensembl_PRO: ENSP00000347294, ENSP00000395916, ENSP00000347434, ENSP00000404558, ENSP00000432770
RefSeq: NP_001357388.1, NP_001287941.1, NP_004091.3, XP_016865861.1, NP_742103.1, NP_001357387.1, NP_001287942.1, XP_016865863.1, XP_016865858.1, XP_016865860.1, NP_742101.2, XP_016865862.1, XP_005266908.1, XP_016865857.1, XP_016865859.1
Others
UniRef100: UniRef100_O95677, UniRef100_B4DRQ6, UniRef100_F2Z2Y1, UniRef100_B4DIV6, UniRef100_O95677-2, UniRef100_O95677-5
UniRef90: UniRef90_B4DIV6, UniRef90_O95677, UniRef90_O95677-5, UniRef90_A0A287AR57
UniRef50: UniRef50_O95677-5, UniRef50_O00167-3, UniRef50_P97767-2, UniRef50_Q9YH98
UniGene: Hs.596680
CCDS: CCDS75523.1, CCDS43506.1, CCDS5166.1, CCDS5165.1

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研究热度

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