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20698 Sphk1

20698

Sphk1

sphingosine kinase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition sphingosine kinase 1

研究结论

Date Results Publications
2021-04-13 10:09:00 Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-delta in sepsis-associated liver injury. 33281190
2021-04-03 13:34:00 K27Q/K29Q mutations in sphingosine kinase 1 attenuate high-fat diet induced obesity and altered glucose homeostasis in mice. 33208918
2021-02-20 13:36:00 The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes. 32764262
2021-01-09 13:32:00 Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells. 32771459
2020-11-21 13:34:00 Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation. 31797978

名称对应

Type IDs
Synonymous 1110006G24Rik, Sk1, Spk1
Gene
UniProtKB-ID: SPHK1_MOUSE
UniprotKB: Q8CI15
UniParc: UPI0000028CCB, UPI00000E5965, UPI00000406AE
EMBL: AK160900, BC037710, AL645851, AF415213, AF068749, AK155332
Ensembl: ENSMUSG00000061878
KO: mmu:20698
Nucleutide sequences
EMBL-CDS: AAC61698.1, BAE36079.1, AAH37710.1, AAL07499.1, BAE33198.1
Ensembl_TRS: ENSMUST00000106387, ENSMUST00000106386, ENSMUST00000106388, ENSMUST00000141798, ENSMUST00000063396, ENSMUST00000100201, ENSMUST00000063446
Protein sequencees
Ensembl_PRO: ENSMUSP00000101996, ENSMUSP00000067865, ENSMUSP00000064743, ENSMUSP00000101995, ENSMUSP00000101994, ENSMUSP00000097775, ENSMUSP00000131010
RefSeq: XP_006532732.1, XP_017169887.1, NP_079643.2, NP_001359414.1, NP_001359417.1, NP_001359413.1, NP_001165943.1, NP_001359418.1, NP_001165946.1, NP_001165944.1, NP_001359415.1, NP_001359416.1, XP_006532735.1
Others
UniRef100: UniRef100_Q8CI15
UniRef90: UniRef90_Q8CI15
UniRef50: UniRef50_Q8CI15
UniGene: Mm.20944
CCDS: CCDS25668.1, CCDS48986.1

全选

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