| Type | Description |
|---|---|
| Definition | trans-acting transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:20:00 | Authors studied the cooperation of Sp1 with its closest paralogue Sp3 in hematopoietic development and demonstrate that Sp1 and Sp3 binding sites largely overlap. | 31164147 |
| 2018-12-22 10:12:00 | Sp3 interacts with the STING promoter and activates the basal transcription of the STING gene. | 28522827 |
| 2017-06-24 11:15:00 | This resulted in Sp1 displacement from the promoter and binding of Sp3 to it, leading to p300 recruitment and histone acetylation, activating transcription. This is the first study addressing the mechanisms of physiological TLR5 expression in the intestine. Additionally, a novel insight is gained into Sp1/Sp3-mediated gene regulation that may apply to other genes | 27060138 |
| 2017-06-24 11:15:00 | Sp3 binds and activates the FGFR4 promoter. | 28359915 |
| 2017-05-20 14:20:00 | Dp71 expression in hepatic cells is carried out, in part, by YY1-, Sp1- and Sp3-mediated transcription from the Dp71 promoter. | 27143785 |
| Type | IDs |
|---|---|
| Synonymous | D130027J01Rik |
| Gene |
UniProtKB-ID:
SP3_MOUSE
UniprotKB:
O70494
UniParc:
UPI00001C270C,
UPI00000E9033,
UPI0000419ECC
EMBL:
AF062567,
AL844840,
AK132702,
AK004607,
BC079874,
BC027797
Ensembl:
ENSMUSG00000027109
KO:
mmu:20687
|
| Nucleutide sequences |
EMBL-CDS:
AAH27797.2,
AAC16322.1,
AAH79874.1,
BAE21310.1,
BAC25090.1
Ensembl_TRS:
ENSMUST00000102689,
ENSMUST00000066003
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099750,
ENSMUSP00000065807
RefSeq:
NP_001091895.1,
NP_001018052.1
|
| Others |
UniRef100:
UniRef100_O70494
UniRef90:
UniRef90_O70494
UniRef50:
UniRef50_O70494
UniGene:
Mm.124328,
Mm.446209,
Mm.465887
CCDS:
CCDS16122.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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