| Type | Description |
|---|---|
| Definition | sortilin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:13:00 | Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes. | 33498179 |
| 2020-06-20 11:40:00 | Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice | 30670473 |
| 2020-04-11 12:43:00 | The Rac-p21-activated kinases 1 to 3 (PAK1-3) have a direct impact on sortilin and each of the three group A kinases binds and phosphorylates a serine residue positioned in a sorting motif within the sortilin cytoplasmic domain. | 31767632 |
| 2019-10-26 10:04:00 | Findings suggest a role of Sortilin (Sort1) in energy regulation and lipid homeostasis in female mice, which may be a potential therapeutic target for obesity and cardiovascular disease. | 29899496 |
| 2019-07-20 11:07:00 | Study shows that retrograde signaling from progranulin to sort1 counteracts synapse elimination in the developing cerebellum. | 29398357 |
| Type | IDs |
|---|---|
| Synonymous | 2900053A11Rik, AI852375, Ntr3, Ntsr3 |
| Gene |
UniProtKB-ID:
SORT_MOUSE
UniprotKB:
Q6PHU5
UniParc:
UPI00001BD7D4,
UPI00005AC65D
EMBL:
BC034129,
AK147442,
BC056343,
AF175279,
AL671899
Ensembl:
ENSMUSG00000068747
KO:
mmu:20661
|
| Nucleutide sequences |
EMBL-CDS:
AAH56343.1,
BAE27915.1,
AAH34129.1,
AAF22639.1
Ensembl_TRS:
ENSMUST00000102632,
ENSMUST00000135636
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099692,
ENSMUSP00000123564
RefSeq:
XP_030108375.1,
XP_030108373.1,
XP_006501287.3,
NP_064356.2,
XP_006501286.3,
NP_001258528.1
|
| Others |
UniRef100:
UniRef100_Q6PHU5
UniRef90:
UniRef90_Q6PHU5
UniRef50:
UniRef50_Q6PHU5
UniGene:
Mm.157119
CCDS:
CCDS80003.1,
CCDS17756.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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