| Type | Description |
|---|---|
| Definition | solute carrier family 36 member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 11:42:00 | SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. | 31555743 |
| 2020-02-29 10:19:00 | Increasing the PAT1 level does not readily increase the mTORC1 activity. The lysosomal PAT1 was increased by starvation and decreased by nutrient replenishment. The lysosomal PAT1 plays a negative role on the mTORC1 activity. | 30253187 |
| 2017-10-14 10:32:00 | A mechanism through which amino acids may suppress the expression of PAT1 on lysosomes by inducing protein cleavage to remove a targeting signal. | 28670736 |
| 2017-06-03 12:11:00 | Data indicate that the glycosylation-deficient mutant of amino acid transporter PAT1 (PAT1(3)(NQ) ) is unstable and is degraded mainly via the endoplasmic reticulum-associated degradation pathway in HEK293 cells. | 28117901 |
| 2014-08-09 10:31:00 | Sertraline is an apparent non-competitive inhibitor of PAT1-mediated transport. | 23962042 |
| Type | IDs |
|---|---|
| Synonymous | Dct1, LYAAT1, PAT1, TRAMD3 |
| Gene |
UniProtKB-ID:
S36A1_HUMAN
UniprotKB:
Q7Z2H8
UniParc:
UPI00001A9D3C,
UPI000000D920,
UPI000000D91E
EMBL:
AY227113,
BX537963,
BK001052,
AY227111,
BC136437,
AY227112,
AF516142,
AY162213,
BC136438,
AC034205,
AK057340
Ensembl:
ENSG00000123643
KO:
hsa:206358
|
| Nucleutide sequences |
EMBL-CDS:
AAI36438.1,
AAI36439.1,
AAO37091.1,
AAO11787.1,
AAO37093.1,
AAO37092.1,
DAA01126.1,
BAB71435.1,
CAD97927.1,
AAP47194.1
Ensembl_TRS:
ENST00000243389,
ENST00000616007,
ENST00000429484,
ENST00000520701
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000395640,
ENSP00000243389,
ENSP00000428140,
ENSP00000480948
RefSeq:
XP_011535882.1,
XP_024310166.1,
XP_016864708.1,
XP_011535894.1,
XP_005268443.1,
XP_011535893.1,
XP_006714822.1,
XP_011535887.1,
XP_024301769.1,
NP_001336669.1,
XP_016864709.1,
XP_011535886.1,
XP_011535883.1,
XP_011535898.2,
XP_024310167.1,
XP_011535888.1,
NP_001295079.1,
XP_011535891.1,
XP_016864705.1,
XP_011535896.1,
XP_011535889.1,
XP_011535885.1,
NP_001295080.1,
XP_016864707.1,
XP_011535897.2,
XP_016864706.1,
XP_011535892.1,
NP_510968.2
|
| Others |
UniRef100:
UniRef100_Q7Z2H8
UniRef90:
UniRef90_Q7Z2H8
UniRef50:
UniRef50_Q7Z2H8
UniGene:
Hs.269004
CCDS:
CCDS78073.1,
CCDS4316.1,
CCDS83035.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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