| Type | Description |
|---|---|
| Definition | SNF related kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:39:00 | Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart. | 31718444 |
| 2020-06-27 10:32:00 | The SNRK regulates insulin signaling through controlling PPP2R5D phosphorylation, which subsequently impacts PP2A activity and then AKT phosphorylation in both WAT and BAT. SNRK may represent a promising potential target for treating insulin resistance-related metabolic disorders. | 31420304 |
| 2019-01-19 11:45:00 | Endothelial cell SNRK/SP1-ITGB1 signaling axis promotes angiogenesis in vivo. | 29242271 |
| 2018-11-24 12:13:00 | Using SNRK transgenic and KO mouse models, study found that SNRK decreases cardiac metabolic substrate usage and mitochondrial coupling, while protecting against ischaemia/reperfusion injury. Effects on substrate usage and cell death are dependent on UCP3, which is downregulated through suppression of PPARalpha by Trib3, a novel binding partner of SNRK. | 28117339 |
| 2017-11-04 12:46:00 | SNRK in cardiomyocytes is responsible for maintaining cardiac metabolic homeostasis, which is mediated in part by ROCK, and alteration of this homeostasis influences cardiac function in the adult heart. | 27780848 |
| Type | IDs |
|---|---|
| Synonymous | 2010012F07Rik, AI448042, AW547029, E030034B15, R74830, mKIAA0096 |
| Gene |
UniProtKB-ID:
SNRK_MOUSE,
B9EK90_MOUSE
UniprotKB:
Q8VDU5,
B9EK90
UniParc:
UPI000002573A,
UPI000192C4E8
EMBL:
BC150742,
BC020189,
BC094658,
AF387809
Ensembl:
ENSMUSG00000038145
KO:
mmu:20623
|
| Nucleutide sequences |
EMBL-CDS:
AAK97440.1,
AAH20189.1,
AAH94658.1,
AAI50743.1
Ensembl_TRS:
ENSMUST00000118886,
ENSMUST00000120173
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114132,
ENSMUSP00000112919
RefSeq:
NP_001344703.1,
NP_001344705.1,
XP_036010649.1,
XP_006512062.1,
XP_036010648.1,
XP_036010647.1,
XP_006512065.1,
XP_006512063.1,
NP_598502.2,
NP_001158044.1,
NP_001344704.1
|
| Others |
UniRef100:
UniRef100_Q8VDU5,
UniRef100_B9EK90
UniRef90:
UniRef90_Q8VDU5
UniRef50:
UniRef50_Q8VDU5
UniGene:
Mm.257989
CCDS:
CCDS23644.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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