| Type | Description |
|---|---|
| Definition | polo like kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 11:01:00 | Plk2 links synaptic overactivity to APP beta-processing, Abeta production, and disease-relevant phenotypes in vivo in Alzheimer's disease model mice | 31306446 |
| 2018-06-23 11:09:00 | Plk2 acts as coordinator of cell proliferation and early lineage commitment in cardiac progenitor cells downstream of Yes-associated protein 1. | 29066438 |
| 2018-05-19 11:36:00 | study demonstrates that PLK-2 activity can rapidly change cellular alpha-synuclein levels in cell models and in mice brains, but this process does not require phosphorylation of S129. Instead, it operates via regulation of alpha-synuclein mRNA transcription in an open reading frame-dependent manner | 28648742 |
| 2017-06-24 11:15:00 | miR-146a regulates lineage negative bone marrow cell senescence and apoptosis by suppressing Plk2 expression that, in turn, activates p16Ink4a/p19Arf and p53 signaling. | 27908889 |
| 2017-06-24 10:44:00 | PLK2, functional kinase and polo-box domains were required for interaction with PFV Gag. Fluorescently-tagged PFV Gag, through its chromatin tethering function, selectively relocalized ectopically expressed eGFP-tagged PLK proteins to mitotic chromosomes i | 27579920 |
| Type | IDs |
|---|---|
| Synonymous | Snk |
| Gene |
UniProtKB-ID:
PLK2_MOUSE,
Q3TV29_MOUSE,
Q548A9_MOUSE
UniprotKB:
P53351,
Q3TV29,
Q548A9
UniParc:
UPI00005B1C29,
UPI0000000D23
EMBL:
AK164365,
AF411834,
M96163,
AK160441
Ensembl:
ENSMUSG00000021701
KO:
mmu:20620
|
| Nucleutide sequences |
EMBL-CDS:
BAE35791.1,
BAE37759.1,
AAL06336.1
Ensembl_TRS:
ENSMUST00000022212
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022212
RefSeq:
NP_690017.2
|
| Others |
UniRef100:
UniRef100_P53351
UniRef90:
UniRef90_Q9NYY3
UniRef50:
UniRef50_Q9NYY3
UniGene:
Mm.380
CCDS:
CCDS26767.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员