| Type | Description |
|---|---|
| Definition | epidermal growth factor receptor pathway substrate 15 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 12:40:00 | Fcho1/2Eps15/RAP-2 ternary complexes to facilitate conformational activation of AP-2 by the Fcho1/2 interdomain linker to promote AP-2 cargo engagement. | 27237791 |
| 2017-06-03 12:25:00 | An interaction of Eps15 and pS227-FIP2 at the appropriate time and location in polarizing cells is necessary for proper establishment of epithelial polarity. | 28228550 |
| 2017-03-04 10:07:00 | RAB11FIP3 combines with Eps15 homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor. | 28215104 |
| 2016-12-24 11:19:00 | Together, the data indicate that a CUL3-SPOPL E3 ubiquitin ligase complex regulates endocytic trafficking and formation of multivesicular bodies by ubiquitinating and degrading EPS15 at endosomes. | 27008177 |
| 2016-12-17 10:05:00 | identify USP9X as a novel regulator of EGFR endocytosis | 26748853 |
| Type | IDs |
|---|---|
| Synonymous | AF-1P, AF1P, MLLT5 |
| Gene |
UniProtKB-ID:
EPS15_HUMAN,
B7Z240_HUMAN
UniprotKB:
P42566,
B7Z240
UniParc:
UPI0000161B29,
UPI0001884446,
UPI0001914B1A
EMBL:
BX647676,
AL671986,
Z29064,
CH471059,
AK294297,
AC104170,
DQ367924,
AK313396,
U07707
Ensembl:
ENSG00000085832
KO:
hsa:2060
|
| Nucleutide sequences |
EMBL-CDS:
EAX06823.1,
CAA82305.1,
BAG36194.1,
ABD34786.1,
AAA52101.1,
BAH11726.1
Ensembl_TRS:
ENST00000371733
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360798
RefSeq:
XP_016856106.1,
XP_016856104.1,
NP_001972.1,
XP_016856105.1,
XP_005270675.1,
NP_001153441.1,
XP_016856109.1,
XP_016856107.1,
XP_016856108.1
|
| Others |
UniRef100:
UniRef100_P42566,
UniRef100_B7Z240
UniRef90:
UniRef90_P42566,
UniRef90_A0A671DUX7
UniRef50:
UniRef50_P42566,
UniRef50_P42566-2
UniGene:
Hs.83722
CCDS:
CCDS557.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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