| Type | Description |
|---|---|
| Definition | sphingomyelin phosphodiesterase 2, neutral |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 10:08:00 | results suggest that SMase-2 deficiency plays a role in the survival or proliferation of liver cancer stem-like cells, leading to spontaneous tumors, which is associated with tumor-specific effects on lipid homeostasis | 29567647 |
| 2011-07-02 10:49:00 | cells deficient in acid ceramidase (aCDase) also exhibited defects in CCL5 induction, whereas cells deficient in sphingosine kinase-1 and -2 exhibited higher levels of CCL5. | 21335555 |
| 2011-04-30 10:23:00 | nSMase2 has a role in ceramide generation, aberrant apoptosis, and lung injury under cigarette smoke exposure | 20448054 |
| 2010-01-21 00:00:00 | NSMase-2 could be involved in IL-1beta-induced JNK activation in hepatocytes | 15059969 |
| 2010-01-21 00:00:00 | Nuclear sphingomyelin-synthase and protein kinase C delta are expressed in melanoma cells | 15907783 |
| Type | IDs |
|---|---|
| Synonymous | AW108287, nSMase, nSMase1 |
| Gene |
UniProtKB-ID:
NSMA_MOUSE
UniprotKB:
O70572
UniParc:
UPI0000021742
EMBL:
AJ222800,
BC010978
Ensembl:
ENSMUSG00000019822
KO:
mmu:20598
|
| Nucleutide sequences |
EMBL-CDS:
CAA10994.1,
AAH10978.1
Ensembl_TRS:
ENSMUST00000019965
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019965
RefSeq:
NP_033239.1,
XP_017169351.1,
XP_030100833.1
|
| Others |
UniRef100:
UniRef100_O70572
UniRef90:
UniRef90_O70572
UniRef50:
UniRef50_Q9ET64
UniGene:
Mm.953
CCDS:
CCDS23805.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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