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20591 Kdm5c

20591

Kdm5c

lysine (K)-specific demethylase 5C

protein-coding

Mus musculus

基因描述

Type Description
Definition lysine (K)-specific demethylase 5C

研究结论

Date Results Publications
2021-02-20 13:35:00 X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity. 32701509
2018-05-26 11:11:00 Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons. 28978483
2017-11-18 10:48:00 The results identify two key regulators, PCGF6 and JARID1c that temper dendritic cells (DC) activation and implicate active transcriptional silencing via histone demethylation as a previously unappreciated mechanism for regulating DC activation and quiescence. 27498878
2017-03-11 10:29:00 Neurite growth in Neuro2a cells was suppressed by the KDM5C mutations associated with intellectual disability in patients. Ntng2 was downregulated in cells with KDM5C mutations, concordant with the lower levels of H3K4 methylation at its promoter. 27421841
2016-02-06 10:32:00 these data suggest that inactivation of JARID1C in renal cancer leads to heterochromatin disruption, genomic rearrangement, and aggressive ccRCCs. 26551685

名称对应

Type IDs
Synonymous D930009K15Rik, Jarid1c, Smcx, mKIAA0234
Gene
UniProtKB-ID: KDM5C_MOUSE
UniprotKB: P41230
UniParc: UPI000000B2F5, UPI000024D9C9, UPI00001929C0
EMBL: AK158340, AK008105, AK129096, AK155427, Z29651, AK155651, AF127245, AF039894, BC043096, AK155279, AK011577, L29563, BC054550
Ensembl: ENSMUSG00000025332
KO: mmu:20591
Nucleutide sequences
EMBL-CDS: CAA82759.1, BAB25462.1, BAE33367.1, AAH43096.1, AAH54550.1, BAE34464.1, BAC97906.1, AAA62384.1, AAD53049.1, AAB96762.1, BAE33260.1, BAE33161.1
Ensembl_TRS: ENSMUST00000112588, ENSMUST00000112584, ENSMUST00000082177
Protein sequencees
Ensembl_PRO: ENSMUSP00000108207, ENSMUSP00000108203, ENSMUSP00000080814
RefSeq: NP_038696.2, XP_006528833.1, XP_006528832.1, XP_036017763.1, XP_017173932.1, XP_006528834.1, XP_006528836.1, XP_030107134.1, XP_017173931.1, XP_006528835.1
Others
UniRef100: UniRef100_P41230
UniRef90: UniRef90_P41230
UniRef50: UniRef50_P41230
UniGene: Mm.142655
CCDS: CCDS41178.1

全选

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