| Type | Description |
|---|---|
| Definition | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 12:19:00 | Data suggest that SWI-SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 protein (SMARCB1)-mediated remodeling of chromatin landscapes is important for the maintenance and differentiation of embryonic stem cells (ESCs). | 31543342 |
| 2019-12-07 11:06:00 | SMARCB1-deficient rhabdoid tumors exhibit dramatic activation of the unfolded protein response and endoplasmic reticulum stress response via a genetically intact MYC-p19(ARF)-p53 axis. | 30753823 |
| 2019-10-26 11:10:00 | Analyses of the Smarcb1 mutant mice indicate that one prominent midline abnormality, corpus callosum agenesis, is due to midline glia aberrations. Study results establish a novel role of Smarcb1 in the development of the brain midline and have important clinical implications for BAF (BRG1/BRM-associated factor) complex-related intellectual disability/neurodevelopmental disorders. | 31273213 |
| 2017-12-09 11:09:00 | Data show that early Smarcb1 loss causes rhabdoid tumors whereas loss at later stages combined with Nf2 gene inactivation causes shwannomas. | 28824165 |
| 2016-06-11 10:54:00 | The occurrence of intracranial rhabdoid tumours depends on control of Smarcb1 inactivation. | 26818002 |
| Type | IDs |
|---|---|
| Synonymous | AU020204, Baf47, Ini1, SNF5/INI1, Snf5 |
| Gene |
UniProtKB-ID:
SNF5_MOUSE,
Q3UDA4_MOUSE,
Q6ZWP4_MOUSE
UniprotKB:
Q9Z0H3,
Q3UDA4,
Q6ZWP4
UniParc:
UPI000002B3E2,
UPI00000019FA
EMBL:
AK150169,
AK075906,
AK145552,
AJ011740,
AJ011739,
BC025163
Ensembl:
ENSMUSG00000000902
KO:
mmu:20587
|
| Nucleutide sequences |
EMBL-CDS:
CAA09760.1,
AAH25163.1,
CAA09761.1,
BAE26504.1,
BAE29357.1,
BAC36045.1
Ensembl_TRS:
ENSMUST00000121304,
ENSMUST00000000925
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112463,
ENSMUSP00000000925
RefSeq:
NP_035548.1,
NP_001155325.1
|
| Others |
UniRef100:
UniRef100_Q12824-2,
UniRef100_Q12824
UniRef90:
UniRef90_Q12824-2,
UniRef90_Q12824
UniRef50:
UniRef50_Q12824-2,
UniRef50_Q12824
UniGene:
Mm.279751,
Mm.405473
CCDS:
CCDS23936.1,
CCDS48602.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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