| Type | Description |
|---|---|
| Definition | helicase-like transcription factor |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 10:54:00 | This is the first study to show Hltf-deletion in an inflammation-associated colorectal cancer model elevates mitochondrial bioenergetics. | 31461471 |
| 2019-01-05 12:14:00 | Findings 1) prove the truncated Hltf protein isoform is a transcription factor, 2) establish a functional link between AS of Hltf and immunosuppression at the feto-maternal interface, 3) correlate intron retention with the absence of DNA methylation, and 4) underscore the importance of differential splicing analysis to identify Hltf's functional diversity. | 29975766 |
| 2014-09-27 12:24:00 | silencing Hltf during heart organogenesis compromised DNA double-strand break repair, and caused aberrant collagen biogenesis altering the structural network that transmits cardiomyocyte force into muscle contraction | 24278285 |
| 2014-01-18 12:01:00 | Data show a role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain | 23826137 |
| 2013-04-20 14:03:00 | p11 and AnxA2 cooperate to create a unique binding pocket, but the optimal binding condition is not achieved without conformational changes associated with target binding. Upon interaction with the SMARCA3 peptide, both Asp60 in p11 and Ser12 in AnxA2 flip inward toward the peptide-binding groove, forming additional intermolecular hydrogen bonds. | 23415230 |
| Type | IDs |
|---|---|
| Synonymous | AF010600, BC057116, P113, Smarca3, Snf2l3 |
| Gene |
UniProtKB-ID:
HLTF_MOUSE
UniprotKB:
Q6PCN7
UniParc:
UPI00001CDE79
EMBL:
BC059240,
AF010138,
BC057116,
BC039796,
AF010600
Ensembl:
ENSMUSG00000002428
KO:
mmu:20585
|
| Nucleutide sequences |
EMBL-CDS:
AAB63915.1,
AAH39796.1,
AAH57116.1,
AAH59240.1,
AAB64175.1
Ensembl_TRS:
ENSMUST00000002502
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002502
RefSeq:
NP_033236.2,
XP_036018883.1,
XP_006535492.1,
NP_001342026.1
|
| Others |
UniRef100:
UniRef100_Q6PCN7
UniRef90:
UniRef90_Q6PCN7
UniRef50:
UniRef50_Q14527
UniGene:
Mm.209650
CCDS:
CCDS17261.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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