| Type | Description |
|---|---|
| Definition | glutamyl-prolyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2019-01-26 10:42:00 | The human glutamyl-prolyl-tRNA synthetase (EPRS) consisting of two fused synthetases .This study identified site-selective proteolysis as a mechanism that severs the linkage between the EPRS synthetases in vitro and in vivo Caspase action targeted Asp-929 in the third WHEP domain, thereby separating the two synthetases. | 29643180 |
| 2018-12-22 10:31:00 | five different EPRS mutations were identified. | 29576217 |
| 2018-02-17 10:56:00 | Data indicate the necessity of EPRS for proliferation of tamoxifen-resistant estrogen receptor (ER+) breast cancer, but not ER- breast cancer cells. | 27612429 |
| 2016-04-23 11:32:00 | analysis of the heterotetrameric complex structure of the glutathione transferase (GST) domains shared among the four MSC components, methionyl-tRNA synthetase (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS), AIMP2 and AIMP3 | 26472928 |
| 2012-06-09 10:26:00 | Dynamic model simulations predicted an inhibitory GAIT-element-interacting factor to account for this relationship and led to the identification of a truncated form of EPRS, a GAIT constituent that mediates binding to target transcripts. | 22386318 |
| Type | IDs |
|---|---|
| Synonymous | EARS, GLUPRORS, HLD15, PARS, PIG32, QARS, QPRS |
| Gene |
UniProtKB-ID:
SYEP_HUMAN
UniprotKB:
P07814
UniParc:
UPI0000205E8C
EMBL:
AC103590,
X07466,
BC136465,
BC034797,
X54326,
BC015494,
BC046156,
CR933648,
AY493416,
BC058921,
BC126275
Ensembl:
ENSG00000136628
KO:
hsa:2058
|
| Nucleutide sequences |
EMBL-CDS:
AAH46156.1,
AAI36466.1,
AAH15494.1,
CAA38224.1,
CAI45949.1,
CAA30354.1,
AAS72877.1,
AAI26276.1,
AAH58921.1,
AAH34797.1
Gene_ORFName:
PIG32
Ensembl_TRS:
ENST00000366923
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355890
RefSeq:
NP_004437.2,
XP_016856103.1
|
| Others |
UniRef100:
UniRef100_P07814
UniRef90:
UniRef90_P07814
UniRef50:
UniRef50_P07814
UniGene:
Hs.497788
CCDS:
CCDS31027.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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