| Type | Description |
|---|---|
| Definition | secretory leukocyte peptidase inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:26:00 | Mecp2 Upregulates Slpi to Reduce Obesity by Enhancing Browning of adipocytes. This is a novel non-central nervous system function of Mecp2 in obesity by suppressing browning, at least partially, through regulating adipokine Slpi. | 31597640 |
| 2020-07-11 12:14:00 | we propose a novel anti-inflammatory mechanism induced by SLPI, which inhibits the ATP-dependent maturation and secretion of IL-1beta. | 31019507 |
| 2018-04-28 10:43:00 | We demonstrate by silencing the SLPI gene, that SLPI negatively regulates human periodontal ligament cell expression of the pro-inflammatory cytokines IL-6 and MCP-1. | 28597116 |
| 2017-10-07 12:27:00 | MIF-2/D-DT is an early response cytokine in the I/R injury repair of the proximal tubule, enhancing regeneration through SLPI- and ATF4-dependent mechanisms. | 28539339 |
| 2017-06-24 12:02:00 | Slpi(-/-) mice had impaired collagen gene expression but animals demonstrated minimal reduction in lung fibrosis compared with wild-type animals. These data suggest that enhanced proteolysis does not further enhance TGF-beta activation, and inhibits sustained Col1alpha1, Col3alpha1, and Col4alpha1 gene expression following lung injury. | 26974397 |
| Type | IDs |
|---|---|
| Synonymous | ALP |
| Gene |
UniProtKB-ID:
SLPI_MOUSE,
Q548X8_MOUSE
UniprotKB:
P97430,
Q548X8
UniParc:
UPI00000000CF
EMBL:
AF205374,
U73004,
BC028509,
AF002719,
U88093,
U94341
Ensembl:
ENSMUSG00000017002
KO:
mmu:20568
|
| Nucleutide sequences |
EMBL-CDS:
AAH28509.1,
AAC53140.1,
AAC53394.1,
AAC53047.1,
AAD09307.1,
AAF19194.1
Ensembl_TRS:
ENSMUST00000109367
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104992
RefSeq:
XP_036015799.1,
NP_035544.1,
XP_036015798.1
|
| Others |
UniRef100:
UniRef100_P97430
UniRef90:
UniRef90_P97430
UniRef50:
UniRef50_P97430
UniGene:
Mm.371583
CCDS:
CCDS17033.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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