| Type | Description |
|---|---|
| Definition | slit guidance ligand 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:34:00 | Slit3 is required for interaction with Robo1 on Schwann cells and fibroblasts in the nerve bridge to control cell migration and axon guidance. | 30726731 |
| 2019-09-14 11:35:00 | these results indicate that SLIT3 plays an osteoprotective role by synchronously stimulating bone formation and inhibiting bone resorption, making it a potential therapeutic target for metabolic bone diseases. | 29504949 |
| 2019-05-18 12:37:00 | these indicate that SLIT3/ROBO2 promotes chondrocyte maturation via the inhibition of beta-catenin signaling. | 30389141 |
| 2018-10-20 12:08:00 | A small truncated recombinant SLIT3 protein increased bone mass in an osteopenic mouse model. | 29764562 |
| 2017-08-19 11:48:00 | While Slit1 and Robo2 are only expressed in peripheral axons and their cell bodies, Slit2, Slit3 and Robo1 are also expressed in satellite cells of the dorsal root ganglion, Schwann cells and fibroblasts of peripheral nerves. | 28234971 |
| Type | IDs |
|---|---|
| Synonymous | Slil2, Slit1, b2b2362.1Clo |
| Gene |
UniProtKB-ID:
SLIT3_MOUSE,
Q3UHN1_MOUSE,
B2RX06_MOUSE,
Q9Z0Y6_MOUSE
UniprotKB:
Q9WVB4,
Q3UHN1,
B2RX06,
Q9Z0Y6
UniParc:
UPI00000E6B4C,
UPI0001747AB3,
UPI00001C4A8B,
UPI00005AC626
EMBL:
BC150780,
AL732630,
AL669856,
AF144629,
AF088902,
AL731688,
AL669839,
AL732401,
AK147292
Ensembl:
ENSMUSG00000056427
KO:
mmu:20564
|
| Nucleutide sequences |
EMBL-CDS:
AAD44760.1,
BAE27826.1,
AAI50781.1,
AAD19349.1
Ensembl_TRS:
ENSMUST00000069837
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000066857
RefSeq:
NP_035542.2
|
| Others |
UniRef100:
UniRef100_B2RX06,
UniRef100_Q3UHN1,
UniRef100_Q9WVB4,
UniRef100_Q9Z0Y6
UniRef90:
UniRef90_O75094,
UniRef90_Q9Z0Y6
UniRef50:
UniRef50_Q9Z0Y6,
UniRef50_O75094
UniGene:
Mm.478604
CCDS:
CCDS24542.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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