| Type | Description |
|---|---|
| Definition | schlafen 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 10:37:00 | Overall, these data suggest that Slfn2 is required for normal osteoclast differentiation and that loss of its function in mice results in an osteopetrotic phenotype. | 30158544 |
| 2019-06-22 11:14:00 | we provide evidence that targeted disruption of the Slfn2 gene leads to increased transcription of IFN-stimulated genes (ISGs) and enhanced type I IFN-mediated antiviral responses | 29866656 |
| 2018-01-13 13:39:00 | there is a functional connection between Slfn2 induced quiescence in T cells and endoplasmic reticulum homeostasis, which shows a novel mechanism by which immune cell quiescence is maintained | 27276683 |
| 2017-10-21 12:16:00 | Regulation of cholesterol levels through the prevention of endoplasmic reticulum stress is an essential component of the mechanism by which Slfn2 regulates T-cell quiescence. | 28672048 |
| 2014-01-25 11:11:00 | several mouse Slfn genes are up-regulated in response to IFN treatment of mouse melanoma and renal cell carcinoma cells, including Slfn1, Slfn2, Slfn4, Slfn5, and Slfn8. | 24089532 |
| Type | IDs |
|---|---|
| Synonymous | Shlf2 |
| Gene |
UniProtKB-ID:
Q9Z0I6_MOUSE
UniprotKB:
Q9Z0I6
UniParc:
UPI0000024586
EMBL:
LT629151,
AF099973,
BC138749,
LT629148,
AL603745,
BC138750
Ensembl:
ENSMUSG00000072620
KO:
mmu:20556
|
| Nucleutide sequences |
EMBL-CDS:
SDA08583.1,
AAC83826.1,
AAI38751.1,
AAI38750.1,
SDA08563.1
Ensembl_TRS:
ENSMUST00000038038
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035562
RefSeq:
NP_035538.1
|
| Others |
UniRef100:
UniRef100_Q9Z0I6
UniRef90:
UniRef90_Q9Z0I6
UniRef50:
UniRef50_Q9Z0I6
UniGene:
Mm.278689
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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