| Type | Description |
|---|---|
| Definition | schlafen 1 |
| Date | Results | Publications |
|---|---|---|
| 2014-01-25 11:11:00 | several mouse Slfn genes are up-regulated in response to IFN treatment of mouse melanoma and renal cell carcinoma cells, including Slfn1, Slfn2, Slfn4, Slfn5, and Slfn8. | 24089532 |
| 2010-01-21 00:00:00 | Results suggest that Schlafen-1 causes a cell cycle arrest during G1 by inhibiting induction of cyclin D1 by mitogens. | 15946944 |
| 2010-01-21 00:00:00 | Schlafen1 and Schlafen2 failed to inhibit cell proliferation, cause G1 cell cycle arrest, or affect Cyclin D1 level in murine fibroblasts. | 18479948 |
| 2010-01-21 00:00:00 | DnaJB6 is necessary for translocation of Slfn1 into the nucleus, where Slfn1 down-regulates cyclin D1, induces cell-cycle arrest and programmes a quiescent state of T-cells | 18373498 |
| Type | IDs |
|---|---|
| Synonymous | AV316259 |
| Gene |
UniProtKB-ID:
Q9Z0I7_MOUSE
UniprotKB:
Q9Z0I7
UniParc:
UPI000002455C
EMBL:
AF099972,
LT629151,
BC052869,
AL669916
Ensembl:
ENSMUSG00000078763
KO:
mmu:20555
|
| Nucleutide sequences |
EMBL-CDS:
SDA08584.1,
AAC83825.1,
AAH52869.1
Ensembl_TRS:
ENSMUST00000037994
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047782
RefSeq:
NP_035537.1
|
| Others |
UniRef100:
UniRef100_Q9Z0I7
UniRef90:
UniRef90_Q9Z0I7
UniRef50:
UniRef50_Q9Z0I7
UniGene:
Mm.10948
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29528433 |
Int. Immunol. Katsuhiro Nakagawa , Takanori Matsuki , Liang Zhao , Kanako Kuniyoshi , Hiroki Tanaka , Isao Ebina , Kenta J Yoshida , Hiroshi Nabeshima , Kiyoharu Fukushima , Hisashi Kanemaru , Fumihiro Yamane , Takahiro Kawasaki , Tomohisa Machida , Hisamichi Naito , Nobuyuki Takakura , Takashi Satoh , Shizuo Akira |
2018-03-08 | - |
| 27626380 |
High-throughput discovery of novel developmental phenotypes. Nature Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja BuÄan , Stephen A Murray |
2016-09-22 | - |
| 24478334 |
Circ Res Yong Wang , Guoqing Hu , Fang Liu , Xiaobo Wang , Mingfu Wu , John J Schwarz , Jiliang Zhou |
2014-03-14 | - |
| 24194600 |
Nucleic Acids Res. Gautier Koscielny , Gagarine Yaikhom , Vivek Iyer , Terrence F Meehan , Hugh Morgan , Julian Atienza-Herrero , Andrew Blake , Chao-Kung Chen , Richard Easty , Armida Di Fenza , Tanja Fiegel , Mark Grifiths , Alan Horne , Natasha A Karp , Natalja Kurbatova , Jeremy C Mason , Peter Matthews , Darren J Oakley , Asfand Qazi , Jack Regnart , Ahmad Retha , Luis A Santos , Duncan J Sneddon , Jonathan Warren , Henrik Westerberg , Robert J Wilson , David G Melvin , Damian Smedley , Steve D M Brown , Paul Flicek , William C Skarnes , Ann-Marie Mallon , Helen Parkinson |
2014-01-01 | - |
| 24089532 |
J Biol Chem Evangelos Mavrommatis , Ahmet Dirim Arslan , Antonella Sassano , Youjia Hua , Barbara Kroczynska , Leonidas C Platanias |
2013-11-15 | - |
| 22560297 |
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. Dev. Cell Matthew Koss , Alexandre Bolze , Andrea Brendolan , Matilde Saggese , Terence D Capellini , Ekaterina Bojilova , Bertrand Boisson , Owen W J Prall , David A Elliott , Mark Solloway , Elisa Lenti , Chisa Hidaka , Ching-Pin Chang , Nizar Mahlaoui , Richard P Harvey , Jean-Laurent Casanova , Licia Selleri |
2012-05-15 |
Ly76,
E2f4,
Mtbp,
Psmg2,
Ltbp4,
Bmp3,
Amhr2,
Abl1,
Macf1,
Acvr1,
Acvr2a,
Acvrl1,
Ak1,
Amh,
Apbb1,
Atm,
Bglap2,
Bmp1,
Bmp2,
Bmp4,
Bmp5,
Bmp6,
Bmp7,
Gdf2,
Bmpr1a,
Bmpr1b,
Bmpr2,
Brca1,
Brca2,
Camk2a,
Camk2b,
Casp3,
Runx1,
Ccna1,
Ccna2,
Ccnb2,
Ccnd1,
Ccne1,
Ccnf,
Cd79a,
Cdc25a,
Cdk2,
Cdk4,
Cdkn1a,
Cdkn1b,
Cdkn2a,
Cdkn2b,
Chek1,
Chrd,
Col3a1,
Col1a1,
Col1a2,
Gadd45a,
Ddit3,
Dlx2,
Dst,
E2f1,
E2f3,
Lefty1,
Eng,
Mecom,
Fkbp1b,
Fos,
Gdf1,
Gdf3,
Gdf5,
Gsc,
Gt(ROSA)26Sor,
Hus1,
Id1,
Id2,
Igf1,
Igfbp3,
Il6,
Inha,
Inhba,
Inhbb,
Itgb1,
Itgb5,
Itgb7,
Jun,
Junb,
Ltbp2,
Smad1,
Smad2,
Smad3,
Smad4,
Smad5,
Mcm3,
Mcm2,
Mcm4,
Mdm2,
Mki67,
Mre11a,
Msh2,
Myb,
Myc,
Nbl1,
Nek2
|
| 20190759 |
Nat Immunol Michael Berger , Philippe Krebs , Karine Crozat , Xiaohong Li , Ben A Croker , Owen M Siggs , Daniel Popkin , Xin Du , Brian R Lawson , Argyrios N Theofilopoulos , Yu Xia , Kevin Khovananth , Eva Marie Moresco , Takashi Satoh , Osamu Takeuchi , Shizuo Akira , Bruce Beutler |
2010-04-01 | - |
| 19619625 |
Gene Olivia Bustos , Saijal Naik , Gayle Ayers , Claudio Casola , Maria A Perez-Lamigueiro , Paul T Chippindale , Ellen J Pritham , Elena de la Casa-Esperón |
2009-11-01 | - |
| 18373498 |
Biochem. J. Yafeng Zhang , Zhengmin Yang , Yonghao Cao , Shijian Zhang , Hai Li , Ying Huang , Yu-Qiang Ding , Xiaolong Liu |
2008-07-15 |
Ccnd1,
Slfn1,
Dnajb6,
DNAJB6,
CCND1
|
| 18355440 |
Subcellular localization of the Schlafen protein family. Biochem. Biophys. Res. Commun. Brent Neumann , Liang Zhao , Kathleen Murphy , Thomas J Gonda |
2008-05-23 |
Slfn1,
Slfn2,
Slfn4,
Slfn9,
Slfn8,
Slfn5
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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