| Type | Description |
|---|---|
| Definition | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | Control of Slc7a5 sensitivity by the voltage-sensing domain of Kv1 channels. | 33164746 |
| 2021-02-13 13:27:00 | The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer. | 33414552 |
| 2020-08-01 15:25:00 | Deletion or inhibition of LAT1 efficiently controls IL-23- and IL-1beta-induced phosphatidylinositol 3-kinase/AKT/mTOR activation independent of T-cell receptor signaling. | 31605740 |
| 2020-08-01 14:05:00 | Loss of solute carrier transporter 7a5 (Slc7a5) impaired activation of the mechanistic target of rapamycin complex 1 (mTORC1) pathway in osteoclasts, whereas genetic activation of mTORC1 corrected the enhanced osteoclastogenesis and bone loss in Slc7a5-deficient mice. | 31289211 |
| 2019-10-05 12:40:00 | Results thus implicate CD44v in the regulation of insulin secretion and reveal that amino acid transport is rate limiting for such secretion. They further suggest that amino acid transport mediated by LAT1 is a potential therapeutic target for diabetes. | 29434323 |
| Type | IDs |
|---|---|
| Synonymous | 4F2LC, D0H16S474E, LAT1, TA1 |
| Gene |
UniProtKB-ID:
LAT1_MOUSE
UniprotKB:
Q9Z127
UniParc:
UPI00000260FA
EMBL:
AB017189,
AB023409,
BC026131
Ensembl:
ENSMUSG00000040010
KO:
mmu:20539
|
| Nucleutide sequences |
EMBL-CDS:
BAA90556.1,
BAA75520.1,
AAH26131.1
Ensembl_TRS:
ENSMUST00000045557
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041557
RefSeq:
NP_035534.2
|
| Others |
UniRef100:
UniRef100_Q9Z127
UniRef90:
UniRef90_Q01650
UniRef50:
UniRef50_Q01650
UniGene:
Mm.27943
CCDS:
CCDS22730.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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