| Type | Description |
|---|---|
| Definition | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans. | 33416451 |
| 2021-03-20 13:35:00 | Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice. | 33508297 |
| 2020-12-12 13:23:00 | HNF1alpha controls glucagon secretion in pancreatic alpha-cells through modulation of SGLT1. | 32711050 |
| 2020-06-20 10:27:00 | During myocardial ischaemia, AMPK up-regulates SGLT1 through ERK, and SGLT1 interacts with EGFR, which in turn increases and Nox2 activity and oxidative stress in cardiac myocytes. | 30715251 |
| 2020-03-21 10:48:00 | SGLT1 contributes to diabetic hyperfiltration and limits diabetic hypertension. Glucose-driven upregulation of macula densa-NOS1 expression increases GFR to maintain volume balance when enhanced MD glucose delivery indicates upstream saturation of SGLTs and thus hyperreabsorption. | 31091127 |
| Type | IDs |
|---|---|
| Synonymous | Sglt1 |
| Gene |
UniProtKB-ID:
SC5A1_MOUSE,
Q8CCA7_MOUSE,
Q9QXI6_MOUSE
UniprotKB:
Q8C3K6,
Q8CCA7,
Q9QXI6
UniParc:
UPI00000211D3,
UPI00000E93CB,
UPI00000E9EF3
EMBL:
AF208031,
AC102594,
AC122203,
BC003845,
AK085602,
AK033512
Ensembl:
ENSMUSG00000011034
KO:
mmu:20537
|
| Nucleutide sequences |
EMBL-CDS:
BAC39483.1,
BAC28332.1,
AAF17249.1,
AAH03845.1
Ensembl_TRS:
ENSMUST00000011178
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000011178
RefSeq:
NP_062784.3
|
| Others |
UniRef100:
UniRef100_Q8CCA7,
UniRef100_Q8C3K6,
UniRef100_Q9QXI6
UniRef90:
UniRef90_Q8C3K6
UniRef50:
UniRef50_P13866
UniGene:
Mm.25237
CCDS:
CCDS19199.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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