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20536 Slc4a3

20536

Slc4a3

solute carrier family 4 (anion exchanger), member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 4 (anion exchanger), member 3

研究结论

Date Results Publications
2019-02-23 13:33:00 These results support a model in which the AE3 Cl(-)/HCO3(-) exchanger, coupled with parallel Cl(-) and H(+)-extrusion mechanisms and extracellular carbonic anhydrase, is responsible for active transport-mediated disposal of CO2. 28779178
2017-09-30 11:39:00 These findings suggest a new type of neuron-astrocyte communication, based on the expression of AE3 in neurons, which could explain how AE3 reduces seizure susceptibility 27353306
2015-08-15 11:34:00 Ae3 is expressed in murine kidney at very low levels. 25402438
2015-01-24 10:06:00 Report the importance of AE3-mediated Cl-/HCO3- exchange in cardiovascular pH regulation and the development of cardiomyocyte hypertrophy. 25047106
2011-05-14 11:36:00 In the TM180 cardiomyopathy model, loss of AE3 had no apparent anti-hypertrophic effect and led to more rapid decompensation and heart failure. 21056571

名称对应

Type IDs
Synonymous A930038D23Rik, Ae3
Gene
UniProtKB-ID: B3A3_MOUSE, Q9ERP4_MOUSE, Q68EG4_MOUSE
UniprotKB: P16283, Q9ERP4, Q68EG4
UniParc: UPI0000020FA1, UPI0000022830, UPI0000419FE2, UPI000002A4A1, UPI000002A4A0
EMBL: BC080271, AF294651, S69314, M28383, CH466548
Ensembl: ENSMUSG00000006576
KO: mmu:20536
Nucleutide sequences
EMBL-CDS: AAB30140.1, EDL00426.1, AAA37184.1, AAG25582.1, AAG25583.1, AAH80271.1
Ensembl_TRS: ENSMUST00000124341
Protein sequencees
Ensembl_PRO: ENSMUSP00000116747
RefSeq: XP_006496520.1, XP_036018838.1, XP_006496514.1, XP_036018856.1, XP_006496513.1, XP_006496518.1, XP_006496519.1, XP_036018854.1, NP_001344079.1, XP_006496521.1, XP_006496516.1, NP_033234.2, NP_001344078.1, XP_006496517.1, XP_030108248.1, XP_030108247.1
Others
UniRef100: UniRef100_P16283, UniRef100_Q68EG4, UniRef100_Q9ERP4
UniRef90: UniRef90_Q9ERP4, UniRef90_P48751
UniRef50: UniRef50_P48751
UniGene: Mm.5053
CCDS: CCDS15080.1

全选

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