| Type | Description |
|---|---|
| Definition | solute carrier family 4 (anion exchanger), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 12:33:00 | results strongly suggest that Ae2 is a critical factor in the innate response to C. albicans. This study represents an important contribution to a better understanding of how Dectin-1 expression and fungal clearance is regulated. | 27391897 |
| 2017-06-03 11:58:00 | Data indicate a key functional role of anion exchanger 2 (AE2) in the maintenance of the normal physiology of biliary epithelial cells (BEC) and the pathogenic consequences of reduced AE2 expression, including abnormal intrinsic characteristics of BEC and their production of signal molecules that lead to the chronic inflammatory responses in small bile ducts. | 27592379 |
| 2016-08-06 11:47:00 | AE2 deficiency results in intrahepatic T-cell activation and PD-1/PD-L1 mediated deletion, favoring autoimmune cholangitis. | 26396175 |
| 2016-04-16 11:13:00 | GnRH neurons were immunopositive for NKCC1 and AE2. | 26110920 |
| 2014-06-14 11:58:00 | These findings demonstrate that CD8(+) T cells are critically dependent on Ae2 for pHi homeostasis and tuning of cell proliferation and activation. Ae2 thus constitutes a novel target to modulate CD8(+) T-cell responses. | 24515893 |
| Type | IDs |
|---|---|
| Synonymous | Ae2, B3RP |
| Gene |
UniProtKB-ID:
B3A2_MOUSE,
Q3UKP0_MOUSE,
A0A0R4J101_MOUSE,
Q7TPS4_MOUSE,
A0A0R4J1K9_MOUSE,
A0A0R4J1K4_MOUSE
UniprotKB:
P13808,
Q3UKP0,
A0A0R4J101,
Q7TPS4,
A0A0R4J1K9,
A0A0R4J1K4
UniParc:
UPI000002A49E,
UPI0000023063,
UPI000002A49D,
UPI000002A49C,
UPI000002A49B,
UPI00001B053D,
UPI000002912D,
UPI000016C958,
UPI000016C959,
UPI00005AC49E
EMBL:
BC054102,
AC120353,
AK145930,
J04036,
AF255774,
AC113055
Ensembl:
ENSMUSG00000028962
KO:
mmu:20535
|
| Nucleutide sequences |
EMBL-CDS:
AAA65505.1,
AAG23158.1,
AAG23155.1,
AAG23154.1,
AAG23156.1,
AAG23157.1,
BAE26761.1,
AAH54102.1
Ensembl_TRS:
ENSMUST00000080067,
ENSMUST00000115049,
ENSMUST00000115047
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000078972,
ENSMUSP00000110701,
ENSMUSP00000110699
RefSeq:
XP_006535716.1,
NP_033233.2,
XP_006535714.1,
XP_036020831.1,
XP_006535718.1,
XP_006535713.1,
NP_001240821.1,
XP_006535719.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J1K9,
UniRef100_Q3UKP0,
UniRef100_Q7TPS4,
UniRef100_A0A0R4J1K4,
UniRef100_P13808,
UniRef100_A0A0R4J101
UniRef90:
UniRef90_P13808
UniRef50:
UniRef50_P13808
UniGene:
Mm.4580
CCDS:
CCDS19119.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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