| Type | Description |
|---|---|
| Definition | solute carrier family 22 (organic anion/cation transporter), member 12 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:54:00 | Extracellular uric acid levels in the proximal tubule epithelial cells positively regulated URAT1 expression.Renal URAT1 expression increased in hyperuricemic mice. | 31882426 |
| 2017-03-18 12:41:00 | Urat1-Uox double knockout mice are a suitable animal model for renal hypouricemia. | 27906636 |
| 2017-01-28 10:23:00 | Immunostaining and highly-sensitive in situ hybridization was used to assess the distribution of UA transporters: GLUT9/URATv1, ABCG2, and URAT1. Immunostaining for GLUT9 was observed in ependymal cells, neurons, and brain capillaries. Immunostaining for ABCG2 was observed in the choroid plexus epithelium and brain capillaries, but not in ependymal cells. These results were validated by in situ hybridization. | 27955673 |
| 2012-03-24 10:30:00 | The cause of obesity/metabolic syndrome-associated hyperuricemia appears to be associated with the urate reabsorption transporter Urat1 protein enhanced by fat. | 22132989 |
| 2010-09-20 12:36:00 | Although the fractional excretion of urate of knockout mice was tend to higher than that of wildtype mice, the urate reabsorption ability remained in the kidney of knockout mice, indicating a urate reabsorptive transporter other than Urat1. | 20544513 |
| Type | IDs |
|---|---|
| Synonymous | AI987855, OAT4L, Rst, Slc22al2, URAT1 |
| Gene |
UniProtKB-ID:
S22AC_MOUSE,
A0A0R4J1I9_MOUSE
UniprotKB:
Q8CFZ5,
A0A0R4J1I9
UniParc:
UPI00000E8F52,
UPI0000027E6E
EMBL:
AC124394,
BC035927,
AB005451,
AC167245
Ensembl:
ENSMUSG00000061742
KO:
mmu:20521
|
| Nucleutide sequences |
EMBL-CDS:
BAA23875.1,
AAH35927.1
Ensembl_TRS:
ENSMUST00000113451
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109078
RefSeq:
NP_033229.3
|
| Others |
UniRef100:
UniRef100_A0A0R4J1I9,
UniRef100_Q8CFZ5
UniRef90:
UniRef90_Q8CFZ5
UniRef50:
UniRef50_Q96S37
UniGene:
Mm.391146
CCDS:
CCDS29505.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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