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20514 Slc1a5

20514

Slc1a5

solute carrier family 1 (neutral amino acid transporter), member 5

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 1 (neutral amino acid transporter), member 5

研究结论

Date Results Publications
2020-03-07 10:42:00 Studies indicate a mechanism by which transcriptional enhancer factor 1 (TEAD1) promotes vascular smooth muscle cells (VSMCs) proliferation via transcriptional induction of solute carrier family 1 member 5 (SLC1A5). 30801233
2019-10-12 10:04:00 The ability of L-4FPG to penetrate the brain makes this compound a useful tool to further evaluate the function of ASCT1 and ASCT2 transporters in the CNS. 30171039
2017-05-20 14:20:00 Data show that SERT associates with ASCT2 (alanine-serine-cysteine-threonine 2), a member of the solute carrier 1 family co-expressed with SERT in serotonergic neurons and involved in the transport of small neutral amino acids across the plasma membrane. 27143784
2014-07-12 10:45:00 These findings highlight a mechanism of T cell activation involving ASCT2-dependent integration of the T cell receptor signal and a metabolic signaling pathway. 24792914
2010-01-21 00:00:00 ASCT1 and ASCT2 mRNA were expressed in cultured blood-brain barrier[BBB] cells; expression of ASCT2 mRNA was 6.7-fold greater. ASCT2 is localized at the abluminal side of the mouse BBB, suggesting a key role in l-isomer-selective Asp transport at the BBB 14622120

名称对应

Type IDs
Synonymous AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC, Slc1a7
Gene
UniProtKB-ID: Q9ESU7_MOUSE, Q3UFR4_MOUSE
UniprotKB: Q9ESU7, Q3UFR4
UniParc: UPI00005AC7B7, UPI00000E88BC
EMBL: AF246130, BC037462, AC148981, AK148346
Ensembl: ENSMUSG00000001918
KO: mmu:20514
Nucleutide sequences
EMBL-CDS: AAH37462.1, AAG02180.1, BAE28496.1
Ensembl_TRS: ENSMUST00000108496
Protein sequencees
Ensembl_PRO: ENSMUSP00000104136
RefSeq: XP_006539758.1, NP_033227.2
Others
UniRef100: UniRef100_Q3UFR4, UniRef100_Q9ESU7
UniRef90: UniRef90_P51912
UniRef50: UniRef50_Q15758
UniGene: Mm.1056

全选

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