| Type | Description |
|---|---|
| Definition | solute carrier family 18 (vesicular monoamine), member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:59:00 | Study shows that in ChAT::Cre+ rats, vesicular acetylcholine transporter overexpression associates with significant alterations of certain cognitive, motor and affective functions. | 31506825 |
| 2018-05-26 12:03:00 | Aged VAChT-deficient mice showed a decrease in the number of hippocampal neurons and Alzheimer's-Like Pathology. | 27312991 |
| 2018-02-24 11:06:00 | These findings suggest that nitrosylation of VAChT and VGLUT1 may be associated with dysfunctional acetylcholinergic and glutamatergic neurotransmission in Alzheimer's disease. | 27911305 |
| 2017-12-02 10:59:00 | Studied object recognition and spatial location in mice deficient for Vesicular Acetylcholine Transporter (VAChT) within interneurons of the striatum, found: impairment in home cage object recognition with a 15 min retention delay, but not with a 3 h retention delay; no on memory for the location of objects; sex differences in retention | 27233822 |
| 2017-10-28 12:22:00 | VAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctions. Data demonstrate that increasing levels of acetylcholine at the synaptic cleft promote degeneration of adult neuromuscular junction, contributing to age- and disease-related motor deficits. | 27713817 |
| Type | IDs |
|---|---|
| Synonymous | VAChT, VAT |
| Gene |
UniProtKB-ID:
Q3TYJ1_MOUSE
UniprotKB:
Q3TYJ1
UniParc:
UPI0000024D53
EMBL:
AC167565,
BC137705,
BC120498,
AK158592
Ensembl:
ENSMUSG00000100241
KO:
mmu:20508
|
| Nucleutide sequences |
EMBL-CDS:
AAI37706.1,
AAI20499.1,
BAE34572.1
Ensembl_TRS:
ENSMUST00000191501
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000139829
RefSeq:
NP_068358.2
|
| Others |
UniRef100:
UniRef100_Q3TYJ1
UniRef90:
UniRef90_Q62666
UniRef50:
UniRef50_Q16572
UniGene:
Mm.190503
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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