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20502 Slc16a2

20502

Slc16a2

solute carrier family 16 (monocarboxylic acid transporters), member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 16 (monocarboxylic acid transporters), member 2

研究结论

Date Results Publications
2021-04-17 13:37:00 Hippocampal Neurogenesis Requires Cell-Autonomous Thyroid Hormone Signaling. 32302557
2021-04-13 10:13:00 The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy. 33466458
2020-11-21 13:11:00 Adult Mice Lacking Mct8 and Dio2 Proteins Present Alterations in Peripheral Thyroid Hormone Levels and Severe Brain and Motor Skill Impairments. 31359845
2019-10-05 10:25:00 Our data provide solid evidence for a unique gate-keeper function of MCT8 and OATP1C1 in SC activation, underscoring the importance of a finely tuned TH signaling during myogenesis. 29706500
2019-10-05 10:25:00 We report hearing loss in mice with mutations in Slc16a2 and a related gene Slc16a10 (Mct10, Tat1). Deficiency of both transporters results in retarded development of the sensory epithelium similar to impairment caused by hypothyroidism, compounded with a progressive degeneration of cochlear hair cells and loss of endocochlear potential. 29535325

名称对应

Type IDs
Synonymous AW105741, Mct8, Xpct
Gene
UniProtKB-ID: MOT8_MOUSE, Q05BA2_MOUSE
UniprotKB: O70324, Q05BA2
UniParc: UPI0000025669
EMBL: AF045692, BC096587, AB265788, AJ421478, BC080678
Ensembl: ENSMUSG00000033965
KO: mmu:20502
Nucleutide sequences
EMBL-CDS: AAH80678.1, CAD33931.1, AAC40078.1, BAF64537.1, AAH96587.1
Ensembl_TRS: ENSMUST00000042664
Protein sequencees
Ensembl_PRO: ENSMUSP00000037629
RefSeq: NP_033223.2, XP_030107132.1
Others
UniRef100: UniRef100_O70324
UniRef90: UniRef90_P36021
UniRef50: UniRef50_P36021
UniGene: Mm.388973
CCDS: CCDS30330.1

全选

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研究热度

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