| Type | Description |
|---|---|
| Definition | solute carrier family 16 (monocarboxylic acid transporters), member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 12:10:00 | MCT1 deletion in Schwann cells impairs both their glycolytic and mitochondrial functions. | 31453649 |
| 2020-05-16 10:20:00 | Knockdown of MCT1 suppressed glycolysis rate and decreased LPS-induced expression of iNOS, interleukin-1beta (IL-1beta), IL-6, and phosphorylation of in BV2 cells. | 31779643 |
| 2020-04-11 10:57:00 | Antioxidants blocked the effects of MCT1 inhibition on metastasis | 31853067 |
| 2020-02-29 10:57:00 | Deletion of MCT1 also causes morphological changes in the organization of the seminiferous tubules and on Sertoli cell morphology resulting in failure of spermatogenesis with depletion of germ cells and total absence of spermatozoa. | 31073907 |
| 2019-11-30 12:16:00 | Silencing of monocarboxylate transporter-1 (Mct-1) by its siRNA suppressed the expression of marker genes for osteoblast differentiation induced by BMP-2 in mouse myoblastic C2C12 cells and in mouse primary osteoblasts. This suppression was abolished by co-transfection of Trp53 siRNA. Together, these results suggest that Mct-1 functions as a positive regulator of osteoblast differentiation via suppression of p53. | 30002387 |
| Type | IDs |
|---|---|
| Synonymous | AL022710, Mct1 |
| Gene |
UniProtKB-ID:
MOT1_MOUSE,
Q544N9_MOUSE
UniprotKB:
P53986,
Q544N9
UniParc:
UPI000000194C
EMBL:
X82438,
AK161701,
AK033516,
AK166606,
BC014777,
AF058055
Ensembl:
ENSMUSG00000032902
KO:
mmu:20501
|
| Nucleutide sequences |
EMBL-CDS:
AAC13720.1,
AAH14777.1,
CAA57819.1,
BAE38889.1,
BAC28335.1,
BAE36539.1
Ensembl_TRS:
ENSMUST00000046212
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045216
RefSeq:
NP_033222.1
|
| Others |
UniRef100:
UniRef100_P53986
UniRef90:
UniRef90_P53987
UniRef50:
UniRef50_P53985
UniGene:
Mm.9086
CCDS:
CCDS17702.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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