| Type | Description |
|---|---|
| Definition | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:30:00 | NaDC1 expression increased only in the proximal convoluted tubules and proximal straight tubules in knockout mice blocked both the citrate and NaDC1 changes | 31188034 |
| 2013-11-30 12:41:00 | Slc26a6-null mice exhibit increased renal and intestinal sodium-dependent succinate uptake, as well as urinary hyperoxaluria and hypocitraturia, but no change in urinary pH, indicating enhanced transport activity of NaDC-1. | 23833257 |
| 2011-02-26 11:32:00 | The acid-activated pathway mediating stimulation of kidney NaDC-1 activity requires a functional ET(B) receptor in vivo and in vitro. | 20703215 |
| 2010-01-21 00:00:00 | Sodium dicarboxylate cotransporter is involved in regulating levels of various Krebs cycle intermediates in the kidney, although impaired uptake of these intermediates does not significantly affect renal function under normal or ischemic stress. | 17410095 |
| 2010-01-21 00:00:00 | Substrate-dependent inward currents, measured using two-electrode voltage clamp, were similar for glutarate & succinate in Xenopus oocytes expressing mouse NaDC1. Currents evoked by glutarate in rabbit NaDC1 were about 5% of succinate-dependent currents. | 16475819 |
| Type | IDs |
|---|---|
| Synonymous | Nadc-1, Nadc1, mNaDC-1 |
| Gene |
UniProtKB-ID:
S13A2_MOUSE
UniprotKB:
Q9ES88
UniParc:
UPI000002777D
EMBL:
BC013493,
AF201903
Ensembl:
ENSMUSG00000001095
KO:
mmu:20500
|
| Nucleutide sequences |
EMBL-CDS:
AAH13493.1,
AAG15426.1
Ensembl_TRS:
ENSMUST00000001122
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001122
RefSeq:
XP_006532711.1,
XP_006532708.1,
XP_006532710.1,
NP_071856.1,
XP_006532712.1
|
| Others |
UniRef100:
UniRef100_Q9ES88
UniRef90:
UniRef90_Q9ES88
UniRef50:
UniRef50_Q13183
UniGene:
Mm.274058
CCDS:
CCDS25103.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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