| Type | Description |
|---|---|
| Definition | solute carrier family 12, member 7 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-21 10:50:00 | During cell swelling PP1alpha and PP1gamma1 are involved in KCC4 regulation by WNK4, but that the kinase acts upon these phosphatases to inhibit their activity. | 28276587 |
| 2014-01-18 11:56:00 | Data are consistent with a role for KCC4 in salt reabsorption of the thick ascending loop of Henle's loop and acid secretion of the collecting duct. | 24089410 |
| 2013-06-22 11:22:00 | We propose that glycosylation is essential for the surface expression, stabilization, and bioactivity of KCC4 | 23376777 |
| 2011-10-29 10:21:00 | KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity | 21733850 |
| 2010-01-21 00:00:00 | all of the CCCs examined (NKCC1, NKCC2, KCC1, KCC3, and KCC4) can promote NH4(+) translocation, presumably through binding of the ion at the K(+) site | 12657561 |
| Type | IDs |
|---|---|
| Synonymous | AA408796, D13Ertd261e, Kcc4 |
| Gene |
UniProtKB-ID:
S12A7_MOUSE,
B9EIV8_MOUSE
UniprotKB:
Q9WVL3,
B9EIV8
UniParc:
UPI0000021554,
UPI00015B3BF6
EMBL:
BC141107,
AK131129,
AK169950,
AK149750,
AF087436,
AK171498
Ensembl:
ENSMUSG00000017756
KO:
mmu:20499
|
| Nucleutide sequences |
EMBL-CDS:
BAE29061.1,
BAE42491.1,
BAD21379.1,
BAE41477.1,
AAD38328.1,
AAI41108.1
Ensembl_TRS:
ENSMUST00000017900
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000017900
RefSeq:
XP_006517233.1,
XP_006517236.1,
NP_001347623.1,
XP_006517237.1,
XP_006517234.1,
NP_035520.1,
XP_006517238.1
|
| Others |
UniRef100:
UniRef100_Q9WVL3
UniRef90:
UniRef90_Q9WVL3
UniRef50:
UniRef50_Q9WVL3
UniGene:
Mm.275800
CCDS:
CCDS26635.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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