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20497 Slc12a3

20497

Slc12a3

solute carrier family 12, member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 12, member 3

研究结论

Date Results Publications
2021-01-09 13:28:00 Renal Tubule Nedd4-2 Deficiency Stimulates Kir4.1/Kir5.1 and Thiazide-Sensitive NaCl Cotransporter in Distal Convoluted Tubule. 32295826
2020-05-02 10:23:00 Aldosterone acutely activates NCC to modulate renal NaCl excretion. 31253651
2019-10-26 11:33:00 This study reveal that lack of renal NCC causes an aldosterone-mediated upregulation of circulating FGF23. 29483574
2019-09-07 11:43:00 Modulation of WNK4 activity by intracellular chloride [Cl(-)]i is not the sole mechanism for regulating NCC. Increased luminal NaCl delivery upregulates NCC via yet unknown mechanism(s) that may override inhibition of WNK4 by high [Cl(-)]i. 29384416
2019-01-12 11:27:00 Aldosterone promotes increased interaction of NCC and ENaC. 28646163

名称对应

Type IDs
Synonymous AI035291, NCC, NCCT, TSC
Gene
UniProtKB-ID: S12A3_MOUSE, Q543E4_MOUSE
UniprotKB: P59158, Q543E4
UniParc: UPI00000040CA
EMBL: AK052691, BC038612
Ensembl: ENSMUSG00000031766
KO: mmu:20497
Nucleutide sequences
EMBL-CDS: AAH38612.1, BAC35098.1
Ensembl_TRS: ENSMUST00000034218
Protein sequencees
Ensembl_PRO: ENSMUSP00000034218
RefSeq: XP_017168116.1, XP_017168114.1, XP_017168115.1, NP_001192240.1, NP_062288.2
Others
UniRef100: UniRef100_P59158
UniRef90: UniRef90_P59158
UniRef50: UniRef50_P59158
UniGene: Mm.25804
CCDS: CCDS57632.1

全选

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研究热度

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