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20494 Slc10a2

20494

Slc10a2

solute carrier family 10, member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 10, member 2

研究结论

Date Results Publications
2020-01-11 11:35:00 Study in Diversity Outbred mice identified the ileal bile acid transporter Slc10a2 as a candidate gene that regulates both the abundance of Turicibacter sp. and plasma levels of cholic acid. 31465442
2016-09-10 10:46:00 data support the concept that under physiological conditions microbiota stimulate Gata4, which suppresses Asbt expression 26022694
2016-01-16 12:23:00 In Asbt-deficient mice, the lack of bile acid uptake in the distal small intestine, which we recently documented using novel in vivo imaging results in more than 10-fold increased fecal bile acids 26210740
2014-05-10 13:31:00 ileal ASBT protein is degraded by a ubiquitin-dependent pathway in response to enterobacteria-associated bile acids 23872411
2013-11-16 11:12:00 Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt(-/-)apoE(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1). 23880190

名称对应

Type IDs
Synonymous 9130221J18Rik, AI605518, ASBT, IBAT, ISBT
Gene
UniProtKB-ID: NTCP2_MOUSE, Q0VBB8_MOUSE
UniprotKB: P70172, Q0VBB8
UniParc: UPI00000220C5
EMBL: AF266727, AF266724, AB002693, AF271073, BC125290, AF266726, D87059, BC120703, AF266725, AY529655, AB078635, AF266728
Ensembl: ENSMUSG00000023073
KO: mmu:20494
Nucleutide sequences
EMBL-CDS: BAA13237.1, BAA19606.1, AAK55514.1, AAS20611.1, BAB84081.1, AAI25291.1, AAI20704.1
Ensembl_TRS: ENSMUST00000023835
Protein sequencees
Ensembl_PRO: ENSMUSP00000023835
RefSeq: NP_035518.1
Others
UniRef100: UniRef100_P70172
UniRef90: UniRef90_Q62633
UniRef50: UniRef50_Q62633
UniGene: Mm.3500
CCDS: CCDS22089.1

全选

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研究热度

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