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20491 Sla

20491

Sla

src-like adaptor

protein-coding

Mus musculus

基因描述

Type Description
Definition src-like adaptor

研究结论

Date Results Publications
2020-09-12 15:58:00 SLAP Is a Negative Regulator of FcepsilonRI Receptor-Mediated Signaling and Allergic Response. 31156621
2015-03-21 10:12:00 SLAP and SLAP2 are critical inhibitors of platelet (hem)ITAM signaling in the setting of arterial thrombosis and ischemic stroke 25301707
2014-04-12 10:32:00 SLAP is a critical regulator of B-cell development and function and its deficiency leads to decreased autoreactive B cells that are otherwise maintained by inefficient receptor editing or failed negative selection. 24440645
2011-04-30 10:42:00 Src-like adaptor protein (SLAP) functions as a negative regulator of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) generation of monocyte-derived dendritic cells of bone marrow origin. 21220694
2011-04-30 10:23:00 SLAP deficiency dramatically reduces both the incidence and severity of arthritis and prevents development of chronic arthritis in the double SKG (mutant ZAP70) Src-like adapter protein (SLAP) knockout mouse model. 21248251

名称对应

Type IDs
Synonymous Slap, Slap-1
Gene
UniProtKB-ID: SLAP1_MOUSE, A0A0R4J247_MOUSE, Q4FJX0_MOUSE
UniprotKB: Q60898, A0A0R4J247, Q4FJX0
UniParc: UPI0000021EB8, UPI0000191DFB, UPI00000E94EA
EMBL: AC157560, AJ131777, U29056, AK036167, AK037901, AY079449, AK137954, BC032922, AK041565, CT010282, AY079450, AC107859
Ensembl: ENSMUSG00000022372
KO: mmu:20491
Nucleutide sequences
EMBL-CDS: CAB66139.1, AAH32922.1, AAL87537.1, AAA82756.1, BAC29896.1, AAL87538.1, BAC30988.1, BAC29328.1, BAE23522.1, CAJ18490.1
Ensembl_TRS: ENSMUST00000100572, ENSMUST00000164163, ENSMUST00000168589, ENSMUST00000168522
Protein sequencees
Ensembl_PRO: ENSMUSP00000098138, ENSMUSP00000127901, ENSMUSP00000130222, ENSMUSP00000131865
RefSeq: XP_017172011.1, XP_006520731.1, XP_030104293.1, NP_033218.1, XP_036015181.1, NP_001025012.1
Others
UniRef100: UniRef100_A0A0R4J247, UniRef100_Q60898
UniRef90: UniRef90_Q60898, UniRef90_A0A1U7QTE6
UniRef50: UniRef50_Q60898
UniGene: Mm.7601
CCDS: CCDS27509.1

全选

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