| Type | Description |
|---|---|
| Definition | homeodomain interacting protein kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:46:00 | HIPK1, HIPK2 and HIPK3 interact with the components of the carbon catabolite repressor 4 (CCR4)-negative on TATA (NOT) complex, an important regulator of all the major steps in the mRNA metabolism. it has emerged that HIPKs and their related miRNAs are involved in diabetic nephropathy, gastric cancer chemoresistance, cervical cancer progression, and recombinant protein expression in cultured cells. [Review] | 29793420 |
| 2018-09-08 10:39:00 | The data presented here con fi rmed that HIPK1 is involved in the increased expression of recombinant luciferase and the secreted recombinant GPC3-hFc from HEK 293 cells following transfection with miR-22-3p. | 28987030 |
| 2015-09-26 12:35:00 | Analysis of these mutants revealed that HIPK1, HIPK2 and HIPK3 but not HIPK4 are capable of autophosphorylating on other tyrosines | 25630557 |
| 2014-06-21 11:11:00 | PAGE4, a regulator of c-Jun transactivation, is phosphorylated by homeodomain-interacting protein kinase 1. | 24559171 |
| 2014-02-08 10:36:00 | HIPK1 drives p53 activation to limit colorectal cancer cell growth. | 23676219 |
| Type | IDs |
|---|---|
| Synonymous | Myak, Nbak2 |
| Gene |
UniProtKB-ID:
HIPK1_HUMAN,
A0A024R0H9_HUMAN,
B4DZ33_HUMAN
UniprotKB:
Q86Z02,
A0A024R0H9,
B4DZ33
UniParc:
UPI00017A842F,
UPI0000072DD3,
UPI000021BFB2,
UPI000000D74E,
UPI000021BFB1
EMBL:
BC033012,
AB014530,
AL833829,
CH471122,
AK302726,
BC036057,
AL731797,
AB089957,
BC028408,
AL137856
Ensembl:
ENSG00000163349
KO:
hsa:204851
|
| Nucleutide sequences |
EMBL-CDS:
AAH28408.1,
AAH36057.1,
BAA31605.1,
EAW56590.1,
CAD38689.1,
AAH33012.1,
BAC57075.1,
EAW56593.1,
BAG63945.1
Gene_ORFName:
hCG_38644
Ensembl_TRS:
ENST00000369558,
ENST00000369553,
ENST00000340480,
ENST00000426820,
ENST00000369559
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358566,
ENSP00000407442,
ENSP00000358572,
ENSP00000358571,
ENSP00000340956
RefSeq:
NP_001356736.1,
NP_852003.1,
NP_689909.2,
NP_938010.1,
NP_938009.1,
XP_005270668.2,
XP_005270670.1,
XP_005270667.2,
XP_006710506.2,
XP_024309676.1,
NP_001356735.1,
XP_011539279.2
|
| Others |
UniRef100:
UniRef100_A0A024R0H9,
UniRef100_Q86Z02
UniRef90:
UniRef90_Q86Z02,
UniRef90_Q86Z02-2
UniRef50:
UniRef50_Q9QZR5,
UniRef50_Q86Z02
UniGene:
Hs.532363
CCDS:
CCDS867.1,
CCDS41370.1,
CCDS869.1,
CCDS868.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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