| Type | Description |
|---|---|
| Definition | sine oculis-related homeobox 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:39:00 | Heterozygous deletion of Otx2, Vax1, or Six3 is sufficient to produce subfertility. Review shows that that all 3 have reduced numbers of GnRH neurons and are subfertile. However, there is specificity to the subfertility by sex and by mechanisms of action. | 30261489 |
| 2019-12-14 12:06:00 | Six3 and Six6 together directly or indirectly suppress Wnt/beta-catenin signaling but promote retinogenic factors for the maintenance of multipotent neuroretinal progenitors. | 30485816 |
| 2018-12-22 11:54:00 | Six3 is haploinsufficient for main olfactory epithelium development, GnRH neuron migration, and fertility. | 29589282 |
| 2018-08-04 11:56:00 | SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression | 29967281 |
| 2017-10-07 11:02:00 | Six3 in a small population of progenitors expressing Six3-Cre at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice. | 28579317 |
| Type | IDs |
|---|---|
| Synonymous | E130112M24Rik, Six3a, Six3alpha, Six3b, Six3beta |
| Gene |
UniProtKB-ID:
SIX3_MOUSE
UniprotKB:
Q62233
UniParc:
UPI0000028B7C,
UPI000016CCF1
EMBL:
D83145,
X90871,
D83144,
BC098096
Ensembl:
ENSMUSG00000038805
KO:
mmu:20473
|
| Nucleutide sequences |
EMBL-CDS:
AAH98096.1,
CAA62379.1,
BAA11823.1,
BAA11822.1
Ensembl_TRS:
ENSMUST00000175898,
ENSMUST00000176081
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000135677,
ENSMUSP00000135312
RefSeq:
XP_017172856.1,
NP_035511.2
|
| Others |
UniRef100:
UniRef100_Q62233
UniRef90:
UniRef90_Q62233
UniRef50:
UniRef50_Q62233
UniGene:
Mm.370208,
Mm.391586
CCDS:
CCDS50203.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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