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20464 Sim1

20464

Sim1

single-minded family bHLH transcription factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition single-minded family bHLH transcription factor 1

研究结论

Date Results Publications
2020-08-22 15:28:00 The Temporal Neurogenesis Patterning of Spinal p3-V3 Interneurons into Divergent Subpopulation Assemblies. 31826942
2019-12-07 10:41:00 Our study provides novel functional evidence supporting LepRb signaling in Sim1 neurons in the regulation of body weight, core body temperature, and cold-induced adaptive thermogenesis. 30802281
2018-02-24 10:14:00 Data (including data from studies in knockout mice) suggest that expression of Mc4r in Sim1 neurons of arcuate nucleus of hypothalamus, paraventricular hypothalamic nucleus, and amygdala is involved in sexual function; here, expression of Mc4r only on Sim1 neurons reverses sexual deficits seen in Mc4r null mice. (Mc4r = melanocortin 4 receptor; Sim1 = single-minded homolog 1) 29059347
2016-05-21 11:30:00 Results demonstrate that Sim1 is essential for proper migration and the guidance of commissural axons of the spinal V3 interneurons 25652362
2015-06-20 10:51:00 These findings reveal Sim1 as a critical yet previously unrecognized modulator of skeletal homeostasis that functions through a central relay. 25607894

名称对应

Type IDs
Synonymous bHLHe14, mSIM1
Gene
UniProtKB-ID: SIM1_MOUSE
UniprotKB: Q61045
UniParc: UPI000002178C
EMBL: AF038853, AF038855, AF038856, AF038854, AF044913, U40575, D79209, AF038857, AB013491
Ensembl: ENSMUSG00000019913
KO: mmu:20464
Nucleutide sequences
EMBL-CDS: BAA28270.1, BAA11467.1, AAC05481.1, AAA91201.1
Ensembl_TRS: ENSMUST00000020071
Protein sequencees
Ensembl_PRO: ENSMUSP00000020071
RefSeq: XP_006512693.1, XP_006512689.1, XP_006512694.1, XP_006512695.1, NP_035506.2, XP_006512690.1
Others
UniRef100: UniRef100_Q61045
UniRef90: UniRef90_Q61045
UniRef50: UniRef50_Q98SJ5
UniGene: Mm.4774
CCDS: CCDS48556.1

全选

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研究热度

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